Research Associate II, Upstream Antibody Discovery

Twist Bioscience; Quincy (MA); On-site; USD 75,000 - 95,000; Full time

Job summary

Twist Bioscience in Massachusetts is seeking a Research Associate II for upstream antibody discovery to support high-throughput hybridoma workflows, production and expression of antibodies in a lab setting.

You will perform hybridoma generation, mammalian cell culture, transfections, and assist with project timelines, with strong documentation and communication as key skills; this role offers growth and a collaborative, fast-paced environment.

Qualifications

• Bachelor's degree in a scientific discipline.
• Prior laboratory experience preferred, industry setting preferred.
• Mammalian cell culture experience with aseptic technique.
• Knowledge of antibody discovery processes and hybridoma workflows is a plus.
• Ability to troubleshoot scientific processes and communicate clearly.
• Highly organized, detail-oriented, and able to work in a fast-paced environment.

Responsibilities

• Hybridoma generation, culture, scale-up, cryopreservation, and antibody production.
• Mammalian cell culture.
• Transient transfections in mammalian cells to support recombinant expression.
• Media and buffer preparation.
• Management of antibody discovery project timelines and deliverables.
• Cross-functional coordination with project managers.
• Troubleshooting and continuous process improvement.

Skills

Bachelor's degree

Mammalian cell culture

Communication skills

Lab documentation

Independent and team work

Education

Bachelor's degree in a scientific discipline

Job description

Research Associate II, Upstream Antibody Discovery

USA - Quincy, MA

Job Description

We seek a Research Associate to support in vivo antibody discovery using our high-throughput hybridoma process. In this lab-based role, attention to detail, strong documentation and communication skills, and working independently and in group settings will be critical for success. You will work directly with the Upstream Antibody Discovery team on various projects to produce and scale hybridoma cell lines while supporting the recombinant expression of antibodies and antigens.

What You'll Be Doing

• Hybridoma generation, culture, scale-up, cryopreservation, and antibody production
• Mammalian cell culture
• Transcient transfections in mammalian cells to support recombinant expression of antibodies and antigens at a range of scales
• Media and buffer preparation
• Management of antibody discovery project timelines and deliverables
• Cross-functional coordination of workflows within the lab and with project managers
• Troubleshooting and continuous process improvement

What You'll Bring to the Team

• Bachelor's degree in a scientific discipline required
• Prior laboratory experience is strongly preferred, with priority toward experience in an industry setting
• Mammalian cell culture experience with excellent aseptic technique
• Knowledge of antibody discovery processes a plus, with a preference toward understanding hybridoma-based workflows
• Ability to troubleshoot scientific processes
• Excellent written and verbal communication skills
• Highly organized, detail-oriented, and able to operate in a fast-paced environment

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this Massachusetts-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

Massachusetts Pay Range

$75,000 - $95,000 USD

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Twist Bioscience's Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.