Research Associate II/Sr. Research Associate – Surface Chemistry

Sarmal; San Diego (CA); On-site; USD 72,000 - 85,000; Full time

Job summary

Sarmal, a San Diego‑based biotechnology company, seeks a RA2/Senior RA to support production-oriented surface functionalization of a biosensor platform. This hands-on role emphasizes reliable batch execution, documented results, and scaling toward pilot/production ramp with growth into broader experimental support.

Ideal candidates have hands-on lab experience with interfacial materials and nucleotide-based chemistries, plus DOE and basic statistics, in a structured manufacturing-like

Qualifications

• Hands-on experience with interfacial materials (2D surface, microarray, flow cell, nanoparticle, membranes).
• Familiarity with nucleotide-based assay chemistries or biofunctionalized surfaces (oligonucleotide/probe immobilization, hybridization, bioconjugation).
• Proven track record of independent, precise batch/production execution within a structured process or manufacturing pipeline.
• Working knowledge of DOE fundamentals and basic statistical analysis to execute and interpret tests.
• Comfort with structured documentation (batch records, ELN, GDP-style recordkeeping).

Responsibilities

• Execute surface functionalization batch runs per SOPs/batch records independently after onboarding.
• Operate core surface characterization methods (fluorescence, contact angle, EIS/CV) for batch/process characterization.
• Summarize characterization results (thickness, density, uniformity, charge) and flag trends for review.
• Support development of nucleotide-based assay consumables and biofunctionalized surface work.
• Assist with surface deposition/patterning process runs (spin-, dip-, spray-coating; plasma activation).
• Execute DOE test plans designed by scientists and apply basic statistics.
• Log data in lab notebooks/ELN and flag deviations.
• Maintain organized inventory of chemistry consumables and reagents.
• Maintain cleanroom/lab space per site protocols.
• Collaborate with in-house scientists and troubleshoot issues.

Skills

Interfacial materials

DOE fundamentals

Statistical analysis

Lab execution

Education

B.S./M.S. in Chemistry or related field

Job description

Company Overview

Sarmal, Inc. is a San Diego–based biotechnology company developing next-generation genomics and molecular detection platforms. Our work integrates molecular biology, chemistry, and advanced systems engineering to enable faster, more precise, and more accessible genomic insights.

Company Overview

Sarmal, Inc. is a San Diego–based biotechnology company developing next-generation genomics and molecular detection platforms. Our work integrates molecular biology, chemistry, and advanced systems engineering to enable faster, more precise, and more accessible genomic insights.

We are a highly collaborative, R&D-driven team operating in a fast-paced, early-stage environment. Our scientists and engineers work across disciplines to solve complex technical challenges and translate innovation into scalable, real-world applications.

At Sarmal, we value scientific rigor, curiosity, and a builder mindset. We are looking for individuals who are energized by ambiguity, motivated by impact, and excited to help bring breakthrough technologies from concept to reality.

About The Job

Sarmal is seeking a RA2/Senior RA to support production-oriented execution of surface functionalization processes for a biosensor device platform. This is primarily a hands‑on execution role for someone with real industry lab experience — running batch processes against documented procedures largely independently, generating consistent and well‑documented results, and supporting the team's pilot‑scale/production ramp. Strong execution and reliability in the first phase may open the door to broader involvement in experimental/research support work as the program progresses. Not looking for entry‑level/new‑grad candidates.

Key Responsibilities

• Execute surface functionalization batch runs (SAM, silane, hydrogel, brush polymer chemistries) per written SOPs/batch records, working independently after initial onboarding.
• Independently operate the team's core surface characterization methods — fluorescence-based uniformity assays, contact angle, and EIS/CV — for routine batch and process characterization.
• Summarize characterization results (thickness, density, uniformity, charge) and flag trends relevant to assay performance (signal, specificity, non‑specific binding) for scientist review.
• Support development of nucleotide‑based assay consumables and other biofunctionalized surface work (e.g., oligonucleotide/probe immobilization, hybridization assays, bioconjugation in microarray/biointerface contexts).
• Assist with surface deposition/patterning process runs (spin‑coating, dip‑coating, spray‑coating, plasma treatment/activation; exposure to PE‑CVD/CVD or photolithographic patterning a plus).
• Execute DOE test plans designed by scientists, applying basic statistical analysis (ANOVA, regression, or similar) to interpret and summarize results; input into test design as experience builds.
• Log data accurately and promptly in lab notebooks/ELN; flag and help investigate deviations from expected process parameters.
• Maintain organized inventory of chemistry consumables and reagents used in daily runs.
• Maintain cleanroom/lab space per site protocols.
• Work collaboratively with in-house scientists; expected to troubleshoot routine issues independently and elevate non‑routine ones.

Qualifications

• Hands‑on experience working with interfacial materials (2D surface, microarray, flow cell, nanoparticle, membranes, etc.) and executing relevant analytical methods e.g. fluorescence-based uniformity assays, goniometry, etc.
• Familiarity with nucleotide‑based assay chemistries or other biofunctionalized surfaces (e.g., oligonucleotide/probe immobilization, hybridization assays, bioconjugation in microarray/biointerface contexts).
• Demonstrated track record of independent, precise batch/production execution within a structured process or manufacturing pipeline.
• Working knowledge of DOE fundamentals and basic statistical analysis, sufficient to execute and interpret a senior‑designed test plan.
• Comfort with structured documentation (batch records, ELN, GDP‑style recordkeeping).

Education

B.S. or M.S. in Chemistry, Materials Science, Chemical Engineering, bioengineering, or related field, or equivalent industry experience + 2–4 years of hands‑on industry lab experience with surface chemistry, thin‑film deposition, or related wet‑chemistry processes

Benefits & Perks

Sarmal offers a competitive and comprehensive benefits package, including:

• Medical, dental, and vision coverage
• Company‑paid life insurance
• 401(k) retirement plan
• Generous paid time off
• Access to additional voluntary benefits, employee perks, and discount programs
• We are committed to supporting the well‑being of our employees and providing a strong foundation for both professional and personal success.

$72,000 - $85,000 a year

California Pay Transparency Statement.

The anticipated salary range for this position is $72,000 – $85,000, depending on experience and qualifications. Final compensation will be determined based on a variety of factors including, but not limited to, location, relevant experience, skill set, and internal equity considerations.

EEO Statement

Sarmal is an equal opportunity employer committed to building a diverse and inclusive workplace. We do not discriminate based on race, color, religion, sex, gender identity or expression, sexual orientation, national origin, ancestry, age, disability, medical condition, genetic information, marital status, veteran status, or any other characteristic protected by applicable federal, state, or local laws.

Reasonable Accommodation Statement

Sarmal is an equal opportunity employer that values diversity and inclusion. We welcome applicants of all backgrounds and consider all qualified candidates in accordance with applicable laws.

Why Join Sarmal

• Work on cutting‑edge genomics and molecular detection technologies
• Collaborate with a deeply technical, cross‑functional team
• Contribute to foundational platform development at an early stage
• Have visibility into and impact on core technical and strategic decisions
• Help shape the infrastructure, culture, and future direction of the company

Closing Statement

Join us in advancing the next generation of genomic technologies and shaping the future of precision health.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.