Research Associate I, Platform Reagents & Assay Support

BigHat; San Mateo (CA); On-site; USD 75,000 - 88,000; Full time

Benefits offered by this job

Health insurance

Dental coverage

Vision coverage

401(k) with company match

Paid parental leave

Company shutdown days

Job summary

BigHat Biosciences is seeking a Research Associate I in Platform Reagents & Assay Support to power our in‑house reagent manufacturing and QC for the Milliner platform.

You will execute high‑throughput workflows, maintain detailed records, and collaborate on SOPs and process improvements with a multidisciplinary team.

The role requires a BS in Biology or Chemistry with 1+ year of industry experience and hands‑on experience with automated liquid handlers and standard lab practices.

Qualifications

• BS in Biology or Chemistry required; 1+ year of industry experience.
• Experience with reagent manufacturing and QC workflows.
• Hands-on with automated liquid handlers and lab instruments.
• Solid record-keeping and communication in a team setting.

Responsibilities

• Execute high-throughput reagent manufacturing and QC workflows.
• Maintain detailed records of reagent lot manufacturing and QC events.
• Contribute to reagent performance monitoring and troubleshooting.
• Collaborate on SOPs for reagent manufacturing and QC.
• Work with cross-functional teams to improve workflows and systems.
• Operate automated liquid handlers and analytical instruments.

Skills

Biology

Chemistry

Lab techniques

Automated liquid handling

Quality control

Documentation

Multidisciplinary teamwork

Education

BS in Biology or Chemistry

Tools

Hamilton

OpenTrons

Tecan

Agilent systems

LIMS

Job description

Research Associate I, Platform Reagents & Assay Support

Department: Lab Science

Employment Type: Full Time

Location: San Mateo, CA

Description

The role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate I, Platform Reagents & Assay Support (PRAS), role to power our in-house reagent manufacturing and QC efforts supporting our Milliner platform.

Key Responsibilities

• Execute automated and manual high-throughput reagent manufacturing and QC workflows to support data generation across BigHat’s production assay suite.
• Keep detailed records of all reagent lot manufacturing and QC events using BigHat’s documentation tools, and clearly communicate results and challenges.
• Contribute to reagent lot performance monitoring, and assist with troubleshooting efforts as needed.
• Collaborate on the creation of laboratory standard operating procedures (SOPs) for reagent manufacturing and QC.
• Collaborate closely with BigHat team members to identify, design, and implement critical process and operational improvements to workflows and laboratory systems.
• Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.

Skills Knowledge and Expertise

• BS in Biology or Chemistry, with 1+ year(s) of industry experience.
• Experience in reagent manufacturing and quality control, process execution, and troubleshooting.
• Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, OpenTrons, Tecan, Agilent systems). Experience with LIMS is a nice-to-have.
• Experience with molecular biology techniques and general lab practices.
• Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
• Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
• Excellent record keeping abilities to document experimental work and analytical data.
• Nice-to-haves include previous experience working with barcoding systems and automated tube/plate labelers, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.)

Total Rewards

The salary estimated for this position is $75,000 - $88,000 + bonus + options + benefits. Compensation will vary depending on job‑related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What BigHat Offers:

• Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
• Dental, and vision coverage through Guardian
• Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
• 401(k) with company match
• DTO, two weeks of company-wide shutdown, and 12 company holidays
• Paid parental leave