Research Associate I – Connectomics

Allen Institute; Seattle (WA); In loco; USD 54.000 - 66.000; Tempo pieno

Vantaggi offerti da questo lavoro

Benefits package

401k

Descrizione del lavoro

The Allen Institute is seeking a Research Associate I to join the light microscopy team in the Connectomics Department, Seattle. The role focuses on connecting anatomy and connectivity with molecular identities, using tissue expansion and volumetric lightsheet imaging for fluorescence.

You will work in a collaborative, team-science environment and contribute to open science initiatives. Ideal candidates hold a Bachelor's in a relevant field and have experience with microscopy, molecular biology,

Competenze

• Bachelor’s degree in neuroscience, biology, bioengineering, biochemistry, molecular biology, or related field.
• Experience in molecular biology, histology, fluorescence microscopy, or image processing.
• Ability to work independently and within a collaborative, multi-disciplinary environment.
• Excellent organizational and communication skills.
• Willingness to follow PPE and safety protocols when handling hazardous substances.

Mansioni

• Perform tissue dissections and preparation of mouse brain samples for profiling and imaging workflows.
• Execute tissue expansion and lightsheet fluorescence microscopy experiments.
• Maintain accurate lab documentation and experimental records.
• Contribute to optimization, troubleshooting, and quality control of workflows.
• Coordinate with internal teams and core facilities to support data generation.
• Present results and summarize progress within the team.
• Follow SOPs and good laboratory practices and regulatory requirements.

Conoscenze

Laboratory work

Organizational skills

Communication skills

Team collaboration

Attention to detail

Self-motivated

Formazione

Bachelor's degree in neuroscience, biology, bioengineering, biochemistry, molecular biology, or related field

Strumenti

Light microscopy

Fluorescence imaging

Tissue expansion workflows

Descrizione del lavoro

The Allen Institute accelerates science for a healthier world through large-scale research designed to answer some of the most complex questions in biology. Our multi-disciplinary teams generate foundational knowledge, tools, and data to understand how our brain, cells, and immune system work. We share our work openly so others can build on it, move faster, and ask bigger questions. We drive discovery forward and create new possibilities for improving human health.

The goal of our Brain Science accelerator is to produce three interlocking resources: cell type atlases that catalog every kind of brain cell across ages and species, connectomes that chart the brain's intricate wiring, and a knowledge platform that knits it all together with powerful analysis tools. Every dataset is freely shared, so discoveries made here fuel discoveries everywhere.

We are seeking a Research Associate I to join the light microscopy team in the Connectomics Department, which aims to link anatomy and connectivity of neurons with their molecular identities and organization at the level of synapses, cells, and neuronal circuits. The Research Associate will contribute to our work to optimize and scale light microscopy-based connectomics in a research program combining tissue expansion and advanced volumetric lightsheet microscopy for fluorescence imaging of ultrastructure with molecular contrast. The successful candidate will be highly organized, self-motivated, and excited to work in a collaborative, team science-oriented environment. This position offers the opportunity to contribute to the nascent and rapidly developing discipline of light-based connectomics, as well as first-hand experience with cutting-edge tools, data, and insights from the connectomics field.

At the Allen Institute, we believe that science is for everyone - and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.

We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

Please include a cover letter with your application describing your career goals and interest in this position.

Essential Functions

• Perform tissue dissections and biochemical preparation of mouse brain samples for downstream molecular profiling and imaging workflows
• Execute experimental workflows for tissue expansion and lightsheet fluorescence microscopy
• Maintain accurate laboratory documentation and experimental records
• Contribute to optimization, troubleshooting, and quality control of experimental workflows
• Coordinate with internal teams and core facilities to support large-scale data and sample generation
• Present results and summarize experimental progress within the team
• Follow SOPs, good laboratory practices, and regulatory requirements

*Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.*

Required Education and Experience

• Bachelor’s degree in neuroscience, biology, bioengineering, biochemistry, molecular biology, or related field

Preferred Education and Experience

• Experience in one or more of the following: molecular biology or biochemistry, mouse tissue processing and histology, fluorescence microscopy, optics or imaging or image processing
• Basic knowledge of neuroanatomy
• Ability to work independently and within a collaborative, multi-disciplinary environment
• Excellent organizational and communication skills
• Positive attitude, self-starter, demonstrated attention to detail, and enthusiasm for learning new experimental approaches
• Laboratory environment - possible chemical, biological, or other hazardous substances exposure
• Work requires proper use of personal protective equipment and engineering controls
• Laboratory duties involve safely handling or working near chemical, biological or other hazardous substances

Physical Demands

• Occasional lifting up to 30 pounds
• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
• Push/pull a cart
• Stooping, bending, crouching
• Reaching or climbing ladders

Position Type/Expected Hours of Work

• This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with the flexibility to work remotely on a limited basis.

Additional Comments

• **Please note, this opportunity does not sponsor work visas**

Annualized Salary Range

• $ 54,250 - $66,450 *

* Final salary depends on the required education for the role, experience, level of skills relevant to the role, and work location, where applicable.

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits .

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.