Research Associate, Department of Neuroscience

The Rector & Visitors of the University of Virginia; Charlottesville (VA); Sur place; USD 52 000 - 68 000; Plein temps

Résumé du poste

The University of Virginia School of Medicine’s Department of Neuroscience seeks a mass spectrometry focused Postdoctoral Research Associate to join the Flowers Lab. The project investigates APOE-related pathways in Alzheimer’s disease using MS, iPSC and clinical samples to identify early biomarkers and targets.

The successful candidate will work in a collaborative environment with access to state-of-the-art instrumentation and NIH-funded resources; the position is for 12 months with renewal

Qualifications

• PhD in Biochemistry, Biophysics, Neuroscience or related field by start date.
• Experience with mass spectrometry sample preparation, instrumentation operation and method development (preferably Sciex).
• Experience in quantitative mass spectrometry, glycomics, glycoproteomics or advanced glycation end products is ideal.
• Experience in Alzheimer’s disease, APOE research or carbohydrate cell metabolism highly regarded.
• Ability to work independently and in a diverse, supportive team.

Responsabilités

• Join the Flowers Lab to carry out fundamental and translational research to improve AD patient outcomes.
• Expand MS and biochemistry skills and strengthen grant and manuscript writing abilities.

Connaissances

MS sample prep

MS instrumentation

MS method development

Data analysis

Glycomics

Glycoproteomics

AD research

APOE research

Team collaboration

Formation

PhD in Biochemistry

PhD in Biophysics

PhD in Neuroscience

Outils

Sciex instruments

Description du poste

Overview

The Department of Neuroscience at the University of Virginia School of Medicine seeks a mass spectrometry focused Postdoctoral Research Associate to join the lab of Dr. Sarah Flowers. The Flowers Lab (flowerslab.org) is focused on Alzheimer’s disease with an interest in APOE, the most significant genetic risk factor for sporadic AD. We utilize mass spectrometry to understand how carbohydrate modifications are altered in AD, and use induced pluripotent stem cells and clinical samples to harness this knowledge for the identification of AD before pathology as well as therapeutic targets to stop the progression to AD. The lab is NIH‑funded and equipped with state‑of‑the‑art instrumentation.

Role & Responsibilities

Our new lab member will join and contribute to a welcoming and supportive environment driven to carry out fundamental and translational research to improve AD patient outcomes. UVA is home to a strong and connected Postdoc community and the successful candidate will have support from the Flowers Lab, the Department of Neuroscience, the Center for Brain Immunology and Glia, and a wide array of UVA programs for professional development. They will expand their MS and biochemistry skills, become confident in the AD field, and improve grant and manuscript writing skills. The position is a 12‑month appointment with the possibility of renewal contingent upon satisfactory performance and the availability of funding. This is a restricted position; continuation is dependent on funding and satisfactory performance. This position has a start date of ASAP and will remain open until filled. This is an exempt‑level, benefitted position.

Qualifications & Experience

• A PhD in Biochemistry, Biophysics, Neuroscience or related field conferred by the start date.
• Experience with mass spectrometry sample preparation, instrumentation operation and method development preferably using Sciex instrumentation, and data analysis.
• Previous research experience focused on quantitative mass spectrometry, glycomics, glycoproteomics or advanced glycation end products is ideal.
• Previous experience in Alzheimer’s disease, APOE research or carbohydrate cell metabolism would be highly regarded.
• The ability to work independently, collaborate with a range of scientists and work as part of a diverse and supportive group is essential.

Employment Details

Postdoctoral employment is temporary and is normally limited to an individual who has been awarded a PhD or equivalent doctorate within the previous five years and who will be involved in full‑time research or scholarship at the University. Employment as a Postdoctoral Research Associate is viewed as training and is preparatory for a full‑time academic or research career, is supervised by a senior scholar, and allows the appointee to publish the results of his/her research or scholarship during the training period.

Equal Opportunity Statement

The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA's commitment to non‑discrimination and equal opportunity employment.