Research Associate - Cardiac Gene Therapy

Baylor College of Medicine; Houston (TX); On-site; USD 68,000 - 73,000; Full time

Job summary

Baylor College of Medicine is seeking a Research Associate in Cardiac Gene Therapy to join the Laboratory for Translational Therapeutics in Houston, TX. This onsite role focuses on controlling immunomodulation for heart and lung fibrosis and novel CRISPR approaches to bioenergetic deficiencies.

You will own research projects with planning, execution, and supervision of vital tasks using in vitro and in vivo models, with emphasis on independent project advancement and collaboration with

Qualifications

• Master's degree required; experience in lieu of degree will not be accepted.

Responsibilities

• Independently performs rodent surgeries for cardiovascular disease models (e.g., LAD ligation).
• Plans and executes molecular cloning workflows with minimal oversight.
• Performs in vitro experiments and routine tissue culture to support vector production.
• Acquires, processes, and analyzes in vivo/ex vivo data including cardiac measurements.
• May supervise and coordinate activities of less experienced research staff.
• Performs other job related duties as assigned.

Education

Master's degree in Basic Science or related field

PhD in a related field

Job description

Job Title: Research Associate - Cardiac Gene Therapy

Division: Surgery

Work Arrangement: Onsite only

Location: Houston, TX

Salary Range: $68,000 - $73,000

FLSA Status: Exempt

Work Schedule: Monday – Friday, 8 a.m. – 5 p.m.

Summary

Step into a pivotal role as a Research Associate and help drive groundbreaking discoveries! You will be an integral part of the Laboratory for Translational Therapeutics, passionately supporting our mission to develop innovative strategies for treating human disease. In this dynamic position, you will be at the forefront of exciting science, focusing on controlling immunomodulation to reduce heart and lung fibrosis and harnessing novel CRISPR systems to conquer bioenergetic deficiencies. You will take ownership of your research, directly shaping our success through the expert planning, execution, and occasional supervision of vital projects using in vitro and in vivo models. Applicants with any experience in at least one of the following are encouraged to apply: cardiovascular biology, gene therapies or surgical animal models.

Job Duties

• Independently performs rodent (rat/mouse) survival and non-survival surgeries for cardiovascular disease models (e.g., LAD ligation, intramyocardial injection)
• Plans and executes molecular cloning workflows (e.g., PCR, Gibson assembly, plasmid preparation) with minimal oversight
• Performs in vitro experiments and routine tissue culture (e.g., transfection, cell line maintenance) to support vector production and independent experimental aims
• Acquires, processes, and analyzes in vivo and ex vivo data, including cardiac functional measurements (e.g., echocardiography, ECG, IVIS imaging) and tissue-based analyses following harvest (e.g., IF, IHC)
• May supervise, schedule and coordinate the activities of less experienced research staff
• Provides occasional supervision and task delegation; titles overseen may include undergraduate student researchers
• Performs other job related duties as assigned.

Minimum Qualifications

• Master's degree in Basic Science or a related field.Experience in lieu of degree will not be accepted.
• Three years of relevant experience typically as a Research Assistant, Research Technician or Postdoctoral Fellow/Associate.

Preferred Qualifications

• PhD in a related field
• Experience with animal surgery
• Experience with molecular cloning workflows (e.g., PCR, Gibson assembly, plasmid preparation)
• Background in cardiovascular biology or cardiomyopathies

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.