Research Area Specialist Intermediate (underfill Associate)

Michigan Medicine; Ann Arbor (MI); Hybrid; USD 55,000 - 75,000; Full time

Job summary

Michigan Medicine in Ann Arbor seeks a researcher to study endoplasmic reticulum protein quality control in multiple myeloma. Work includes mammalian cell culture, immunoblotting, flow cytometry, proteomics, and patient biospecimen analysis.

You will assist the PI with experimental design and data presentation at weekly lab meetings. Requires a Bachelor's degree + 4–5 years (Associate 1–3 years); Masters/PhD preferred. Hybrid work options may be available within a large academic health system.

Qualifications

• Bachelor's degree required with 4–5 years of related experience (Associate level requires 1–3 years).
• Masters or doctoral degree preferred.

Responsibilities

• Perform and support biomedical research experiments to study endoplasmic reticulum protein quality control pathways in multiple myeloma.
• Implement xenotransplant and syngeneic multiple myeloma studies to evaluate novel inhibitors and genetic manipulation.
• Collect, analyze and interpret experimental data with increasing independence; troubleshoot results and improve data collection.
• Assist the Principal Investigator with development of research goals, experimental design, technical decision-making, and presentation of data at weekly lab meetings.
• Assist with ordering supplies, maintaining safety protocols and standard operating procedures, organizing laboratory materials, and ensuring efficient laboratory operations.

Education

Bachelor's degree

Masters or doctoral degree preferred

Job description

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Responsibilities*

• Perform and support biomedical research experiments to study and develop novel therapeutic approaches for endoplasmic reticulum protein quality control pathways in multiple myeloma, including mammalian cell culture, immunoblotting, cell viability assays, flow cytometry, proteomics and primary patient biospecimen analysis.
• Implement xenotransplant and syngeneic multiple myeloma studies to evaluate novel small molecule inhibitors and genetic manipulation of ER protein quality control pathways, including tumor monitoring, tissue collection, biochemical analysis, and maintenance of genetic lines.
• Collect, analyze, and interpret experimental data with increasing independence, including identifying trends, troubleshooting results, and suggesting improvements to data collection and measurement approaches.
• Assist the Principal Investigator with development of research goals, experimental design, technical decision-making, and presentation of data and research plans at weekly laboratory meetings.
• Assist with ordering supplies, maintaining safety protocols and standard operating procedures, organizing laboratory materials, and ensuring the laboratory functions efficiently and safely.

Required Qualifications*

Intermediate Level

• Bachelors degree
• 4-5 years of related experience

Associate Level

• Bachelors degree
• 1-3 years of experience in related field

Desired Qualifications*

• Masters or doctoral degree preferred.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world's most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

Underfill Statement

This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO Statement

The University of Michigan is an Equal Opportunity Employer. We are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants, including protected veterans and individuals with disabilities.