Remote Senior Principal Scientific Advisor – Nonclinical

Charles River; Wilmington, Northern (MA, KY); Hybrid; USD 220,000 - 240,000; Full time

Benefits offered by this job

Bonus incentives

401K

Health coverage

Stock purchase program

Work-life balance

Job summary

Charles River is seeking a Senior Principal Scientific Advisor to lead nonclinical pharmacology and toxicology programs within Safety Assessment. The role focuses on strategic scientific guidance from discovery through FIH and clinical development, working with multidisciplinary teams and clients.

The ideal candidate has 20+ years in pharma/biotech nonclinical development, direct toxicology experience, and demonstrated leadership in regulatory interactions and program management.

Qualifications

• Minimum 20 years’ experience in pharmaceutical/biotech sector, nonclinical contract research or consulting including at least 12 years nonclinical drug development experience.
• Must have direct experience in regulated toxicology and drug development.
• Prior direct experience in interacting with regulatory agencies is preferable.
• Prior experience in program management and/or Pharm/Tox Program Leadership is considered useful.

Responsibilities

• Provide strategic scientific guidance for the advancement of innovative medicines from discovery through first-in-human (FIH) studies and clinical development.
• Lead cross-functional teams and client interactions to integrate discovery and safety programs.
• Develop and implement nonclinical pharmacology and toxicology strategies that support regulatory milestones and global registration objectives.

Skills

Nonclinical drug development

Regulatory interactions

Project leadership

GLP familiarity

Education

Professional certification: DABT/DACVP/ERTO

Tools

Microsoft Excel

Microsoft Word

PowerPoint

Job description

Charles River is seeking a Senior Principal Scientific Advisor to lead nonclinical pharmacology and toxicology programs within Safety Assessment. The role focuses on strategic scientific guidance from discovery through FIH and clinical development, working with multidisciplinary teams and clients.

The ideal candidate has 20+ years in pharma/biotech nonclinical development, direct toxicology experience, and demonstrated leadership in regulatory interactions and program management.