Remote Senior Full-Stack Engineer — AI-Driven SaaS

Worky; United States; On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Fully remote

Flexible schedules

Generous vacation policy

Health coverage

Annual bonus

Job summary

Simulations Plus is a global leader in model-informed and AI-accelerated drug development, offering fully remote work and flexible schedules. The Senior Full-Stack Engineer will contribute across the full stack, including backend, frontend, and AI surfaces, in a lean, rapidly growing team.

The role emphasizes building real depth in web platforms and applied-AI engineering, with a culture that cares about employee well-being and flexible work arrangements.

Qualifications

• 3+ years of professional software engineering experience with shipped full-stack work in production.
• Proficiency in JavaScript/TypeScript across Node.js backend and React frontend.
• Experience with document or NoSQL databases such as MongoDB.
• Comfort building and consuming REST APIs and JSON contracts.
• Genuine interest in agents, MCP, and applied AI, and the drive to build real expertise.

Responsibilities

• Own features end-to-end across Node.js backends and React frontends.
• Build the APIs, UI, and data flows behind real customer-facing functionality.
• Contribute to the data, auth, and service patterns the platform builds on.
• Integrate LLM-powered functionality into product surfaces, wiring frontends to LLM endpoints.
• Contribute to evals, fixtures, and tooling that support the AI side of the team.
• Bring full-stack range to a team that values flexibility across backend, frontend, and AI.

Skills

JavaScript/TypeScript

Node.js

React

REST APIs

NoSQL MongoDB

AI tooling

AI/ML familiarity

Education

Bachelor's degree in Computer Science or related field

Tools

AWS

CI/CD

OAuth/OIDC

Job description

Simulations Plus is a global leader in model-informed and AI-accelerated drug development, offering fully remote work and flexible schedules. The Senior Full-Stack Engineer will contribute across the full stack, including backend, frontend, and AI surfaces, in a lean, rapidly growing team.

The role emphasizes building real depth in web platforms and applied-AI engineering, with a culture that cares about employee well-being and flexible work arrangements.