Remote Senior Bioinformatics Scientist — NGS Pipelines

Socket.dev; United States; On-site; USD 117,400 - 146,800; Full time

Job summary

Natera is seeking a Senior Bioinformatics Scientist to lead architecture, development, and automation of high-throughput genomic pipelines. You will build production-grade tools to analyze NGS data including variant calling, fusion detection, and QC metrics.

The role requires strong Python, Nextflow or WDL, and cloud experience to design scalable workflows in a fast-paced, mission-driven environment. Remote USA options are available.

Qualifications

• Ph.D. in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field; 0–3 years of professional experience.
• Master’s in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field; 4–6 years of professional experience.
• Deep understanding of high-throughput DNA sequence data analysis including mapping, alignment, and variant calling workflows.
• Strong Python programming skills with NumPy, Pandas, and Scikit-learn.

Responsibilities

• Analyze complex genomic datasets leveraging scaled in-house pipelines and collaborate with wet-lab scientists and statisticians.
• Architect, build, and deploy automated analysis pipelines for diagnostic tests with fusion detection, variant calling, and QC metrics.
• Develop novel genomic analysis tools and optimize pipeline accuracy and efficiency.
• Participate in code reviews and documentation for core computational workflows.
• Coordinate with infrastructure teams to scale R&D tools into production systems.

Skills

Python

Nextflow

AWS

Linux

Genomics data analysis

Education

Ph.D. in Bioinformatics, CS, Eng or related field

Master’s in Bioinformatics, CS, Eng or related field

Tools

NumPy

Pandas

Scikit-learn

MySQL

S3

Job description

Natera is seeking a Senior Bioinformatics Scientist to lead architecture, development, and automation of high-throughput genomic pipelines. You will build production-grade tools to analyze NGS data including variant calling, fusion detection, and QC metrics.

The role requires strong Python, Nextflow or WDL, and cloud experience to design scalable workflows in a fast-paced, mission-driven environment. Remote USA options are available.