Remote-Eligible Patient Safety PVSci Manager

Vertex Pharmaceuticals LLC; Boston (MA); Hybrid; USD 121,000 - 181,000; Full time

Benefits offered by this job

Medical, dental, vision benefits

Commuting subsidy

401(k)

Job summary

Vertex Pharmaceuticals LLC is seeking a Global Patient Safety (GPS) Pharmacovigilance Science (PVSci) Manager in Boston, MA. The role leads cross-functional safety monitoring, aggregate reporting, and signal management to support regulatory submissions and patient safety programs.

You will drive safety data review, develop safety content for study reports and regulatory requests, and coordinate timelines across GPS teams.

Qualifications

• Advanced healthcare degree or equivalent professional experience.
• Minimum of 2 years pharmacovigilance or relevant experience with data analysis and medical/scientific writing.
• Preference for aggregate/periodic safety report preparation.

Responsibilities

• Leads PVSci activities for assigned Vertex product, coordinating safety data review and timely issue communication.
• Prepares aggregate safety report content including risk management plans and regulatory responses.
• Conducts signal detection, tracking and risk management activities.
• Provides project management support across GPS functions with timelines and planning.
• Develops meeting materials for GPS safety discussions and cross-functional forums.
• Supports safety content development per program strategy and timelines.

Skills

Project management

Data analysis

Medical writing

Cross-functional collaboration

Pharmacovigilance

Electronic systems

Continuous learning

Education

Advanced healthcare degree

Tools

Safety database

Job description

Vertex Pharmaceuticals LLC is seeking a Global Patient Safety (GPS) Pharmacovigilance Science (PVSci) Manager in Boston, MA. The role leads cross-functional safety monitoring, aggregate reporting, and signal management to support regulatory submissions and patient safety programs.

You will drive safety data review, develop safety content for study reports and regulatory requests, and coordinate timelines across GPS teams.