Remote - Biostatistician III

The Fountain Group; San Francisco (CA); Ibrido; USD 102.000 - 109.000; Tempo pieno

Descrizione del lavoro

The Fountain Group is seeking a senior statistics professional for a 3-month contract (with extension possible) to support clinical development programs. You will independently develop, program, and execute analyses and simulations using SAS, with opportunities to use R for additional work.

Key tasks include Monte Carlo simulations, power calculations, MI techniques, and multiplicity adjustments, leveraging SDTM/ADaM datasets. Strong PhD or equivalent experience is highly valued.

Competenze

• Advanced degree in Statistics, Biostatistics, or related field; PhD preferred.
• Strong SAS programming experience and ability to run analyses independently.
• Experience with statistical simulations, power calculations, and Type I error control.
• Experience implementing multiple imputation and multiplicity adjustments.
• Familiarity with SDTM and ADaM datasets for clinical trials.
• Ability to communicate statistical approaches and results clearly.

Mansioni

• Independently develop, program, and execute statistical analyses and simulations for clinical programs.
• Perform SAS-based analyses, including Monte Carlo simulations and power calculations.
• Implement multiple imputation techniques to handle missing data.
• Develop multiplicity adjustment methods and control FWER as needed.
• Work with CDISC SDTM and ADaM datasets and validate results through simulations.
• Collaborate with cross-functional clinical development and statistics teams to meet deliverables.

Conoscenze

SAS programming

Statistical simulations

Monte Carlo simulations

Power calculations

Multiple imputation

Multiplicity adjustment

CDISC SDTM/ADaM

R programming

Formazione

Advanced degree in Statistics/Biostatistics; PhD strongly preferred

Strumenti

SAS

R

Descrizione del lavoro

Details for the positionare as follows:

• 3-month contract to start with the possibility of extension depending on performance and business needs
• Rate: $74-79 an hour
• Location: 100% remote

Job Description:

• Independently develop, program, and execute statistical analyses and simulations to support clinical development programs.
• Perform statistical simulations, including Monte Carlo simulations, power calculations, and Type I error evaluations.
• Implement multiple imputation (MI) techniques to address missing data in clinical trial analyses.
• Develop and apply multiplicity adjustment methods, including family-wise error rate (FWER) control.
• Utilize SAS as the primary statistical programming language, with opportunities to leverage R for additional statistical analyses and simulations.
• Extract, manipulate, and analyze clinical trial data from CDISC SDTM and ADaM datasets.
• Validate statistical methods and analytical results through simulations and independent programming.
• Apply advanced statistical methodologies to support clinical study objectives and analytical deliverables.
• Collaborate with clinical development and statistical teams to ensure accurate, timely completion of assigned projects.
• Independently develop, program, and execute statistical analyses and simulations to support clinical development programs.
• Perform statistical simulations, including Monte Carlo simulations, power calculations, and Type I error evaluations.
• Implement multiple imputation (MI) techniques to address missing data in clinical trial analyses.
• Develop and apply multiplicity adjustment methods, including family-wise error rate (FWER) control.
• Utilize SAS as the primary statistical programming language, with opportunities to leverage R for additional statistical analyses and simulations.
• Extract, manipulate, and analyze clinical trial data from CDISC SDTM and ADaM datasets.
• Validate statistical methods and analytical results through simulations and independent programming.
• Apply advanced statistical methodologies to support clinical study objectives and analytical deliverables.
• Collaborate with clinical development and statistical teams to ensure accurate, timely completion of assigned projects.

Required Skills:

• Advanced degree in Statistics, Biostatistics, or a closely related quantitative field. PhD strongly preferred; exceptional candidates with a Master's degree and extensive relevant experience will also be considered.
• Strong hands-on SAS programming experience, including independently developing and executing statistical analyses.
• Experience performing statistical simulations, particularly power calculations, Type I error control, and Monte Carlo methods.
• Experience implementing multiple imputation and multiplicity adjustments.
• Familiarity with clinical trial datasets, including SDTM and ADaM.
• Strong understanding of statistical methodologies and the ability to independently develop, execute, and validate analyses.
• Ability to communicate statistical approaches, methodologies, and results effectively.

Preferred Qualifications

• Experience within pharmaceutical, biotechnology, CRO, or clinical research environments.
• Proficiency in R programming in addition to SAS.
• Experience supporting or executing Statistical Analysis Plans (SAPs).
• Experience collaborating with clinical development and cross-functional research teams.
• Previous experience performing advanced statistical programming and simulations in clinical research settings.