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Hy-Vee in Yankton, SD is hiring a Registered Nurse (RN) in the Pharmacy department. Use clinical expertise to support pharmacists in vaccine administration, prescription preparation, and patient care.
The RN will engage with customers, handle offsite vaccination events, maintain patient information and HIPAA compliance, and help ensure safe, high-quality service in a fast-paced retail setting. A nursing degree and state licensure are required; the role offers teamwork, growth opportunities, and
We promise “a helpful smile in every aisle” and those smiles can only come from a workforce that is fully engaged and committed to supporting our customers and each other.
Job Title: Registered Nurse (RN)
Department: Pharmacy
FLSA: Hourly
Revision Date: 07/2026
At Hy‑Vee, we believe the shortest distance between two people is a smile. We're seeking people with a passion for customer service, a willingness to learn, and a commitment to being part of a team that strives to make our customers' lives easier, healthier and happier.
Our Registered Nurses bring clinical expertise to the pharmacy setting, supporting pharmacists in vaccine administration, prescription preparation, and patient care. In this role, you'll assist with a wide range of pharmacy functions while applying your nursing knowledge to deliver safe, high-quality service to every customer. If you are a licensed RN who is passionate about community health, comfortable in a fast‑paced retail environment, and committed to exceptional patient care, we'd love to have you on our team.
Accountable and Reports to: Store Director; Store Manager; Assistant Managers of Health Wellness Home, Store Operations, and Perishables; Pharmacy Department Manager; Staff Pharmacists
Physical activity is incidental to the core duties of the role. Ability to occasionally walk the floor or facility to observe operations, staff, or product. Ability to occasionally handle product for demonstration purposes. Exposure to bloodborne pathogens and sharps (needles, lancets) associated with vaccine and immunization administration and other direct patient care duties. No regular lifting, carrying, or physical exertion required.
This is a fast‑paced role in a retail pharmacy where you will handle multiple tasks throughout your shift including vaccine administration, prescription support, and customer service. There is occasional exposure to hazardous chemicals or solvents during compounding, including chemotherapy drugs. When working offsite for vaccination events, you may be exposed to equipment movement hazards, temperature extremes, vibrations, and dampness. Safety is always a priority, and training is provided to help ensure a safe and supportive work environment.
Are you ready to smile, apply today.
Employment is contingent upon the successful completion of a pre employment drug screen.