Regenerative Medicine Imaging Scientist for Wound & Vascular Repair

University of Pittsburgh; Pittsburgh (Allegheny County); On-site; USD 90,000 - 120,000; Full time

Job summary

The University of Pittsburgh Department of Surgery invites applications for the Research Assistant Professor faculty position. The successful candidate will contribute to collaborative research programs using cutting-edge imaging and molecular technologies to advance regenerative medicine, wound healing, and vascular repair at MIRM.

The role emphasizes in vivo rodent models, perfusion imaging, single-cell profiling, and epigenetic gene-editing strategies such as TNT.

Qualifications

• Must have a doctoral degree (Ph.D.) in Biological Sciences, Biochemistry, Cell/Molecular Biology, or a related field.
• Demonstrated expertise in diabetic and chronic wound healing, including impaired-perfusion and ischemic wound models, using in vivo rodent models and human tissue.
• Specific experience with cutaneous vascular biology - angiogenesis, vasculogenesis, endothelial and fibroblast reprogramming, and in vivo tissue-perfusion assessment.
• Hands-on experience with cutting-edge imaging technologies applied to skin and vasculature, such as in vivo wound-perfusion imaging (e.g., laser speckle), high-resolution confocal and multiphoton microscopy, and single-cell molecular profiling of tissue.
• Experience with epigenetic and gene-regulatory approaches - DNA methylation/demethylation (e.g., TET-mediated), RNA methylation, epigenetic gene editing, and epithelial-mesenchymal transition biology.
• Experience with primary skin cell and ex vivo/organotypic skin work (fibroblast, endothelial, and keratinocyte culture and reprogramming).
• 5+ years of research experience in an academic research environment.
• Must be willing to work with animals and human subjects.
• Must be able to multitask and show interest in contributing to several concurrent projects in the Center.
• Tissue Nanotransfection (TNT) technology experience required.
• Electronic Lab Notebook (e.g., LabGuru) experience preferred.

Responsibilities

• The qualified scientist will play a major role in a dynamic program in basic and translational research applying cutting-edge imaging and molecular reprogramming technologies to regenerative medicine, wound healing, and vascular repair at MIRM.
• The faculty member will use pre-clinical rodent models - supported by advanced in vivo perfusion imaging and single-cell/spatial molecular profiling - to study impaired diabetic and ischemic wound healing and to develop tissue-reprogramming and epigenetic gene-editing strategies (including TNT-based approaches) that restore perfusion and drive tissue repair.
• As this is a supporting role, the faculty member will partner with interdisciplinary scientists toward translational program building but will not be expected to have regular teaching or service responsibilities external to their research group.
• A successful candidate will also actively support grant submissions and submit grants as PI.
• We offer a competitive academic salary, fringe benefits, and state-of-the-art facilities.

Skills

Diabetic wound healing

In vivo rodent models

Cutaneous vascular biology

Imaging technologies

Epigenetic gene regulation

Primary skin cell culture

Lab management experience

TNT-based approaches

Education

PhD in Biological Sciences / Biochemistry / Cell biology or related field

Tools

Electronic Lab Notebook (LabGuru)

Job description

The University of Pittsburgh Department of Surgery invites applications for the Research Assistant Professor faculty position. The successful candidate will contribute to collaborative research programs using cutting-edge imaging and molecular technologies to advance regenerative medicine, wound healing, and vascular repair at MIRM.

The role emphasizes in vivo rodent models, perfusion imaging, single-cell profiling, and epigenetic gene-editing strategies such as TNT.