QC Analyst

TALENT Software Services; Novato (CA); On-site; USD 65,000 - 85,000; Full time

Job summary

TALENT Software Services is seeking a Quality Control Analytical In-Process (QCA-IP) Analyst to perform analytical test methods on in-process intermediates and various drug product stages under minimal supervision and cGMP guidelines. This role will involve knowledge including protein determination by A280, Bradford, UV absorbance, enzyme activity, HPLC/UPLC, and method validation.

You will support manufacturing for clinical and commercial therapeutics, interpret results, contribute to trend

Qualifications

• Bachelor of Science degree.
• 0-3 years of relevant laboratory experience; QC experience preferred.
• Experience with quality management systems and GMP.
• Good documentation and communication skills.
• Ability to work with minimal supervision.
• Proficiency in Word and Excel; PowerPoint preferred.
• Familiarity with scheduling systems (BINOCS) and SAP preferred.
• Willingness to work additional hours to meet production needs.

Responsibilities

• Timely facilitation of incoming sample receipt and accessioning flow.
• Execute analytical methods for in-process testing under cGMP guidelines.
• Evaluate assay validity, summarize results, analyze data, and assist with trend analysis.
• Share general housekeeping tasks and maintain inspection readiness.
• Monitor and control laboratory reagent inventories.
• Qualify as trainer for specified methods and train less experienced staff.
• Communicate compliance risks and initiate investigations when needed.
• Support method validation, investigations, and transfer protocols.
• Attend team meetings and suggest lab infrastructure improvements.
• Identify opportunities to improve operational efficiency.
• Perform other responsibilities as deemed necessary.

Education

Bachelor of Science degree

Tools

Excel

BINOCS

SAP

Job description

PURPOSE

The Quality Control Analytical In-Process (QCA-IP) Analyst is responsible for performing analytical test methods on in-process intermediates and varying stages of drug products under minimal supervision and within cGMP guidelines, to support further manufacturing of commercial and clinical therapeutics. This role will involve knowledge that includes but is not limited to the following analyses and concepts: Protein determination by A280, Bradford, UV Absorbance, Enzyme activity, HPLC/UPLC, and method validation.

CHARACTERISTICS

Functional activities may include: performing a wide variety of analytical assays, maintaining test sample throughput, monitoring lab supplies, preparing reagents, contributing to process and method validation studies, supporting investigations and equipment validation, and brainstorming further development or improvement ideas for procedures.

Work assignments will vary by degree of complexity. Employee is expected to follow SOPs, make appropriate decisions in daily activities with minimal needs for intervention, and be able to recognize deviations from routine practices. Incumbent must accurately complete tasks on time to achieve lab goals, meanwhile limiting GMP / procedural errors, and be capable of accepting and incorporating feedback. Must also demonstrate the ability to both manage time and prioritize routine work effectively.

Employee must be able to interpret results against defined criteria, begin to apply critical thinking to routine work. He/she should demonstrate an ability to evaluate results against trend reports, serve some degree of troubleshooting and capacity as trainer, and embrace an active role in following up on atypical results or issues. Communication of relevant information must be made to appropriate audiences, and attendance of necessary team meetings with some participation in discussions is essential. Employee should also be actively engaged in his/her role, exhibit frequent volunteerism as the work schedule flow permits and maintain a positive attitude.

Responsibilities

• Timely facilitation of incoming sample receipt and accessioning flow, decipher batch assignments across all assay types in accordance with agreed upon best practices.
• Execute analytical methods to facilitate in-process testing under applicable cGMP guidelines, as well as contribute to the prompt reporting of results to meet the required timetables of internal customers.
• Evaluate completed assay validity, calculate and summarize results, analyze data per expected or specification ranges. Assist with the compilation and verification of trend analysis reports.
• Perform and collaborate with co-workers to appropriately share general housekeeping activity assignments and ensure systems for laboratory maintenance are adequate for creating a consistent state of inspection readiness.
• Assist with monitoring and the control of laboratory supply and critical reagent inventories.
• Qualify as trainer for specified methods, provide training to less experienced staff.
• Exhibit proactive communication upon occurrence of compliance risks and deviations from laboratory procedures, perform initiation of investigation records within required timeframes.
• Provide input or assay support to the progression of test method validation, investigations, technical studies, and method transfer protocols.
• Attend team huddles and department meetings, generate ideas for laboratory infrastructure improvements and method optimization.
• Identify areas to improve operational excellence by reducing non-value-added activities and increasing process efficiency.
• Perform other responsibilities as deemed necessary.

Qualifications

• Bachelor of Science degree.
• 0-3 years of relevant laboratory experience; QC specific experience is preferred.
• Experience with quality management systems, current Good Manufacturing Practices, and QC principles.
• Demonstrated working knowledge with respect to certified functional activities.
• Good documentation, written and verbal communication skills are essential.
• Must possess the ability to perform most tasks with minimal supervision.
• Computer literacy is required, with proficiency in Microsoft Word and Excel, and experience in Microsoft PowerPoint preferred.
• Familiarity with BINOCS or similar scheduling systems is preferred.
• Familiarity with SAP or similar enterprise systems is preferred.
• Must have a quality service attitude and focus, exhibit flexibility and willingness to work additional hours to meet production or laboratory process requirements.