QA Validation Leader - PPQ & CPV for Commercial Pharma

Revolution Medicines; San Francisco (CA); On-site; USD 164,000 - 205,000; Full time

Job summary

Revolution Medicines is seeking a Senior Manager, Quality Validation to lead QA oversight of validation activities across CMOs and external partners, focusing on PPQ and CPV for commercial manufacturing. The role requires extensive GMP knowledge and experience in validation lifecycle management.

The candidate will support broader QA activities, collaborate with cross-functional teams, and ensure compliance with global regulatory requirements.

Qualifications

• Bachelor's degree in a scientific, engineering or technical discipline.
• Minimum 8 years in pharmaceutical GMP Quality and commercial manufacturing operations.
• Strong experience with PPQ/CPV and validation lifecycle principles.

Responsibilities

• Provide QA oversight of validation activities across CMOs and external partners.
• Review validation plans, protocols, reports, risk assessments and change controls.
• Support GMP Quality activities including deviations, investigations, CAPAs, and batch records.
• Lead or support development and inspection readiness activities.
• Build collaborative relationships with internal and external stakeholders.

Skills

QA oversight

Validation lifecycle

PPQ

CPV

GMP knowledge

Education

Bachelor's degree in science/engineering

Job description

Revolution Medicines is seeking a Senior Manager, Quality Validation to lead QA oversight of validation activities across CMOs and external partners, focusing on PPQ and CPV for commercial manufacturing. The role requires extensive GMP knowledge and experience in validation lifecycle management.

The candidate will support broader QA activities, collaborate with cross-functional teams, and ensure compliance with global regulatory requirements.