Project Manager

Arrowhead Pharmaceuticals; San Diego (CA); On-site; USD 105,000 - 125,000; Full time

Benefits offered by this job

Competitive salaries

Excellent benefit package

Job summary

A biopharmaceutical company in San Diego is seeking a Project Manager to lead cross-functional teams developing novel RNAi therapeutics. The ideal candidate will have 5 years of project management experience in a regulated industry and strong proficiency in Smartsheet. This role is office-based five days a week with a salary range of $105,000 to $125,000 USD, along with competitive benefits.

Qualifications

• 5 years of project management experience in a biopharma or regulated industry.
• Experience managing or interacting with CRO/CDMO/3rd-party vendors.
• Excellent communication and influencing skills.

Responsibilities

• Drive cross-functional collaboration for program plans.
• Prepare presentations and reports for stakeholders.
• Monitor progress and identify risks to Program Leadership.

Skills

Smartsheet

Communication skills

Project management

Stakeholder management

Education

Bachelor’s degree in a business-related or life sciences field

Tools

Outlook

Word

Excel

ThinkCell

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical‑stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. Arrowhead’s RNAi‑based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state‑of‑the‑art manufacturing facility in Verona, WI. Our employees are nimble, science‑driven innovators who are collaborating to bring new therapies to patients in need.

Position

The Project Manager is an integral part of several Product Teams and/or Core Teams developing novel RNAi therapeutics for diseases with high unmet need. The Project Manager will work under the Executive Director, Program Management to define and monitor timelines and deliverables. The successful Project Manager will have excellent knowledge in Smartsheet and other program planning and visualization software, good communication skills and enthusiasm for defining and monitoring several program plans and milestones at Arrowhead Pharmaceuticals.

This role is based in San Diego, California, with an expectation to be in office 5 days a week.

Responsibilities

• Drive cross‑functional collaboration to develop and manage integrated early‑phase program plans and timelines.
• Lead and document meetings, capturing and tracking key decisions, action items, and follow‑ups.
• Prepare and deliver presentations, reports, and events to align and engage stakeholders.
• Develop scenario planning models and visualizations to support strategic and operational decisions.
• Coordinate across Product and Program Teams with diverse technical and functional backgrounds.
• Standardize and communicate program timelines across teams and the broader portfolio.
• Manage resources and budgets using Smartsheet or equivalent planning and visualization tools.
• Monitor progress, track deliverables, and proactively identify and elevate risks to Program Leadership.
• Maintain dashboards, portfolio updates, and enterprise‑level progress reports.
• Collaborate within a matrixed organization to integrate program timelines, resolve bottlenecks, and ensure cross‑program alignment.

Requirements

• Bachelor’s degree in a business‑related or life sciences field.
• 5 years of project management experience in a biopharma, medical device or similar regulated industry.
• Experience managing or interacting with CRO/​CDMO/​3rd‑party vendors.
• Prior responsibility for critical technical data/documents and recommendation review.
• Proficient use of IT/program management tools (Outlook; Word; Excel; ThinkCell; Smartsheet superuser status preferred).
• Excellent communication, influencing, stakeholder management, and decision‑making skills.
• Highly motivated team player with a proactive, collaborative approach.

Preferred

• PMP Certification.
• Master’s Degree.

Compensation & Benefits

California pay range: $105,000—$125,000 USD.

Arrowhead provides competitive salaries and an excellent benefit package.

Legal

All applicants must have authorization to work in the US for a company.