Production Chemist - Torrance

polypeptideus; Torrance (CA); On-site; USD 38,572 - 61,992; Full time

Job summary

PolyPeptide is seeking a Production Chemist in Torrance, CA to support the manufacture of high-quality Active Pharmaceutical Ingredients (APIs) in a cGMP-regulated environment. The role spans from executing batch production to maintaining compliance with safety and quality standards.

This is an excellent opportunity for those early in their career or experienced chemists looking to lead. Competitive salary varies based on level, with a clear growth path in peptide synthesis and purification technologies.

Qualifications

• Chemist I: 0–2 years of relevant experience in peptide manufacturing preferred.
• Chemist II: 3+ years of relevant experience in a regulated environment.
• Chemist III: 5+ years of relevant experience with demonstrated leadership.

Responsibilities

• Execute batch production records accurately in compliance with SOPs.
• Operate and monitor chemical processes including reactors and purifications.
• Perform in-process controls and interpret analytical results.
• Ensure proper material handling, inventory management, and documentation.
• Maintain high standards of safety and cleanliness.

Skills

Peptide synthesis and purification (HPLC)

cGMP documentation and compliance

Safe handling of hazardous chemicals and reagents

Strong communication

Teamwork

Time management

Problem-solving

Continuous improvement mindset

Education

Bachelor’s degree in a scientific discipline

High School Diploma with significant GMP manufacturing experience

Job description

Production Chemist

Location: Torrance, CA Employment Type: Full-Time

PolyPeptide is seeking a Production Chemist (I, II, and III) to support the manufacture of high-quality Active Pharmaceutical Ingredients (APIs) in a cGMP-regulated environment. These roles are critical to our mission of delivering safe, effective, and on-time pharmaceutical products to patients worldwide.

Whether you are early in your career or an experienced chemist ready to lead, we offer a clear growth path, hands‑on manufacturing experience, and the opportunity to work with advanced peptide synthesis and purification technologies.

What You’ll Do (All Levels)

As a Production Chemist, you will be responsible for executing and supporting peptide manufacturing operations across upstream synthesis and downstream purification while maintaining strict compliance with cGMP, safety, and quality standards.

Core Responsibilities

• Execute batch production records (BPRs) accurately and in compliance with SOPs and GxP requirements
• Operate and monitor chemical processes including reactors, drying systems, purification HPLCs, and lyophilization
• Perform in-process controls (IPCs) and interpret analytical results (e.g., HPLC, ninhydrin tests)
• Ensure proper material handling, inventory management, and ERP documentation following ALCOA+ principles
• Maintain high standards of safety, cleanliness, PPE usage, and 5S practices
• Communicate effectively with cross-functional teams including QA, QC, Maintenance, Engineering, and Supply Chain

Level-Based Scope & Growth

Production Chemist I

• Entry‑level to early‑career role with hands‑on manufacturing responsibility
• Works under general supervision following established procedures
• Focused on execution, learning cGMP operations, and building technical expertise
• Ideal for candidates new to peptide manufacturing or regulated production environments

Production Chemist II

• Experienced individual contributor with increasing autonomy
• Troubleshoots process deviations, supports investigations, and assists with CAPAs and quality documentation
• Trains and mentors Chemist I team members
• Participates in process improvements, tech transfers, and scale‑up activities

Production Chemist III

• Senior‑level chemist and technical leader
• Acts as a subject matter expert (SME) for processes and equipment
• Makes operational "go/no-go" decisions with Quality and leadership
• Leads troubleshooting, process optimization, and mentoring of Chemist I & II staff
• Supports production planning, forecasting, and continuous improvement initiatives

Qualifications (Level-Appropriate)

Education

• Bachelor’s degree in a scientific discipline or equivalent
• High School Diploma with significant GMP manufacturing experience may be considered (Chemist I)

Experience

• Chemist I: 0–2 years of relevant experience (peptide manufacturing preferred)
• Chemist II: 3+ years of relevant experience in a regulated environment
• Chemist III: 5+ years of relevant experience with demonstrated leadership and technical expertise

Key Skills

• Peptide synthesis and purification (HPLC)
• cGMP documentation and compliance
• Safe handling of hazardous chemicals and reagents
• Strong communication, teamwork, and time management
• Problem‑solving and continuous improvement mindset

Work Environment

• Hands‑on manufacturing environment with hazardous materials
• Ability to wear respirators and required PPE
• Regular standing, walking, and lifting up to 25 lbs

Salary

Production Chemist I: $28-$33/hr

Production Chemist II: $33-$37/hr

Production Chemist III: $37-$45/hr

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.