Process Scientist

Flamma; Malvern (Chester County); On-site; USD 70,000 - 90,000; Full time

Job summary

Flamma is looking for a candidate with a MS or PhD in Organic Chemistry to join their team in Malvern, Chester County, United States. The role involves executing experiments, evaluating process safety, and collaborating with various teams in a GMP environment.

Ideal candidates should have over 2 years of experience in API manufacturing and a solid understanding of analytical instruments. Strong organizational and communication skills are essential for successful execution of this role.

Qualifications

• 2+ years of relevant experience in API manufacturing companies required.
• Familiarity with GMP regulations preferred.

Responsibilities

• Execute experiments to evaluate and develop synthetic routes to small molecule targets.
• Work to determine operational space for various process parameters.
• Evaluate safety of processes utilizing calorimetry and stability data.
• Follow guidance from project leaders or senior scientists for problem-solving.
• Execute scale-up of processes in the kilo labs in a GMP environment.
• Support scale-up of processes in the pilot plant in a GMP environment.
• Collaborate with various teams to ensure successful completion of campaigns.
• Accurately collect reliable data for updates to customers.

Skills

Knowledge of analytical equipment/instruments such as HPLC, GC, DSC, TGA, KF, NMR, LCMS, and GCMS

Excellent organizational skills

Excellent communication skills

Education

MS or PhD in Organic Chemistry

Job description

Responsibilities

• Execute experiments to evaluate and develop synthetic routes to small molecule targets.
• Work to determine operational space for various process parameters to ensure efficient and successful scale up.
• Evaluate safety of processes utilizing calorimetry data and stability data to fully understand the hazards and the trigger points of these hazards.
• Follow guidance from project leader or senior scientists to problem solve complex synthetic problems during development.
• Execute scale up of processes in the kilo labs in a GMP environment.
• Support scale up of processes in the pilot plant in a GMP environment.
• Collaborate with analytical chemists, operations staff, and QA to ensure successful completion of campaigns and release of raw materials, intermediates, and final products.
• Accurately collect reliable data in the form of lab procedures or reports to be used for updates to customers or during drafting of production’s MBR.

Qualifications

• MS, or PhD (Organic Chemistry).
• 2+ years of relevant experience in API manufacturing companies required.
• Knowledge of analytical equipment/instruments such as HPLC, GC, DSC, TGA, KF, NMR, LCMS, and GCMS required.
• Familiarity with GMP regulations preferred.
• Excellent organizational and communication skills required.