Process Engineer, Principal Scientist – Automation of Machinery and Processes

Scorpion Therapeutics; Boston (MA); On-site; USD 180,000 - 240,000; Full time

Job summary

Scorpion Therapeutics in Boston seeks a Principal Process Engineer to lead automation and manufacturing solutions for Cell & Genetic Therapies programs. You will guide equipment and system design, lifecycle management, and technology transfer to ensure compliant, scalable processes.

Requirements include a BS/MS in Engineering with 10+ years in regulated biotech environments and deep knowledge of cell & gene therapy processes.

Qualifications

• BS/MS in Engineering with 10+ years in process/systems engineering in regulated biotech environments.
• Experience leading equipment/system design and lifecycle management.
• Knowledge of cell & gene therapy processes and tech transfer.

Responsibilities

• Provide technical leadership on equipment and system design, lifecycle management, process optimization, and tech transfer.
• Oversee complex equipment development from concept to validation.
• Troubleshoot manufacturing issues and author technical documentation.
• Collaborate cross-functionally with manufacturing, process development, quality, validation, and external vendors.

Skills

Process engineering

Regulated biotech

Leadership

Tech transfer

Education

BS/MS in Engineering

Tools

FMEA

cGxP

Lean Six Sigma

Job description

Role

Principal Process Engineer leading automation and manufacturing solutions for Vertex's Cell & Genetic Therapies programs.

Responsibilities

• providing technical leadership on equipment/system design, lifecycle management, process optimization, and technology transfer
• overseeing complex equipment development from concept to validation
• troubleshooting manufacturing issues
• authoring technical documentation
• collaborating cross-functionally with manufacturing, process development, quality, validation, and external vendors

Requirements

• BS/MS in Engineering with 10+ years (or equivalent)
• extensive experience in process/systems engineering within regulated biotech environments
• knowledge of cell & gene therapy processes

Preferred skills

• expertise in FMEA, risk assessment, cGxP principles, and lean/six sigma methodologies

High-value specifics

• focus on cell & genetic therapy manufacturing, equipment lifecycle management, regulatory compliance, and cross-functional leadership in a fast-paced, innovative setting

Location

On-site five days/week with ad hoc flexibility