Process Engineer, Lilly Medicine Foundry

Initial Therapeutics, Inc.; Indianapolis (IN); On-site; USD 102,960 - 171,600; Full time

Job summary

Lilly Medicines Foundry in Lebanon, Indiana, is hiring a Process Engineer – API Manufacturing to support pilot plant operations for active pharmaceutical ingredients. The role focuses on solving technical challenges, advancing process knowledge, and managing equipment capabilities.

Responsibilities include risk assessments, reactor design learning, safety compliance, and maintaining cgMP-compliant equipment. Collaboration across multiple teams and rigorous documentation are expected.

Qualifications

• BS or MS in chemical engineering or related engineering field.
• Minimum 2 years in pharmaceutical/biotech/CMO process engineering.
• Authorized to work in the United States full-time; no visa sponsorship.

Responsibilities

• Perform impact and risk assessments for unit operations.
• Learn reactor design, automation recipes, and procedures.
• Ensure compliance with safety and company policies.
• Maintain processing equipment per Quality System and cgMP standards.
• Model/simulate heat and mass transfer when scaling to plant.
• Engage with HSE, QA, Tech Services, Development, Operations, Automation, Maintenance.
• Prepare technical reports and regulatory submissions; maintain records.
• Identify quality issues and communicate them appropriately.
• Develop plans and timetables for project work.

Skills

Analytical thinking

Problem solving

Team collaboration

Process control systems

Creativity

Mentoring others

Education

BS or MS in chemical engineering

Tools

DeltaV

Dynochem

Aspen

Electronic lab notebooks

Job description

Process Engineer – API Manufacturing

This position supports the pilot plant facility at the Lilly Medicines Foundry in Lebanon, Indiana, focusing on active pharmaceutical ingredient synthesis. The role involves solving technical challenges with equipment design, developing and sustaining process knowledge, optimizing processes, and managing equipment capabilities.

Responsibilities

• Perform impact and risk assessments for unit operations
• Learn reactor design, automation recipes, and procedures
• Ensure compliance with safety and company policies
• Maintain processing equipment in compliance with internal Quality System, engineering standards, and cGMP requirements
• Assess rig fit by modeling, simulations, or experimental work to validate heat and mass transfer when scaling to plant
• Engage and communicate with HSE, Quality Assurance, Tech Services, Development, Operations, FUME/C&Q, Automation, Maintenance, Environmental Monitoring, and Manufacturing
• Author, review, or approve technical reports and regulatory submissions; maintain records and technical notebooks
• Proactively identify quality issues and communicate appropriately
• Develop or review plans and timetables for project work

Basic Requirements

• BS or MS in chemical engineering or related engineering degree and at least 2 years experience in a pharmaceutical, biotech, or CMO environment supporting process engineering for drug substance API manufacturing or development
• Authorized to work in the United States on a full‑time basis. Lilly does not sponsor work authorization or visas.

Additional Preferences

• Deep technical interest and understanding in the field of Chemical Engineering
• Ability to work well in a team with diverse functional relationships and willingness to be accountable
• Experience with DeltaV, Dynochem, Aspen, and/or electronic lab notebooks
• Strong analytical and problem‑solving skills
• Strong oral and written communication skills for diverse audiences
• Ability to work independently and as part of a process team with management, production, science, and engineering professionals
• Understanding of process control systems
• Creativity to identify improvement opportunities and initiative to implement them
• Guidance/mentoring of others through processes
• Flexibility to meet business needs

Other Information

• Initial location at Parkwood West, Indianapolis.
• Permanent location at the new Lilly Medicines Foundry in Lebanon, Indiana.

Benefits and Compensation

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $66,000 - $171,600.

Full‑time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company‑sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well‑being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion, and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

EEO Statement

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.