Process Development Engineer III, Analytical Science: Synthetic and Bioconjugation Scale-Up

BioSpace; Village of Tarrytown (NY); On-site; USD 110,000 - 179,000; Full time

Benefits offered by this job

Student Loan Paydown

Tuition Reimbursement

Family Care Benefits

Relocation Assistance

Well-being programs

Job summary

Regeneron is seeking a Process Development Engineer III to join the PMPD group's SBST Analytics in Tarrytown, NY. You will serve as the analytical lead, developing fit-for-purpose methods, transferring them to internal/external labs, and troubleshooting to advance bioconjugate programs from development to commercialization.

The role requires strong communication skills and hands-on experience with HPLC/LC-MS/UV, Empower, and cross-functional collaboration with internal teams and CDMOs.

Qualifications

• B.S. with 10+ years of relevant experience, M.S. with 7+ years, or recent Ph.D. with 0-3 years in chemistry, biochemistry, biology, chemical engineering, or a related field
• Hands-on experience with analytical method development for antibody, bioconjugate, and/or small molecules (e.g., HPLC, LC-MS, UV) plus software such as Empower
• Hands-on experience transferring methods to internal/external labs and troubleshooting
• Demonstrated experience serving as analytical lead for bioconjugate programs and collaborating with internal teams and external CDMOs
• Strong written and verbal communication; ability to present data to diverse audiences

Responsibilities

• Independently design and execute analytical testing, method development, and characterization to enable bioconjugate process development
• Lead analytical deliverables: robust method development, method transfer, training, and troubleshooting
• Communicate complex results into clear, actionable next steps for technical and non-technical audiences
• Author procedures, development and characterization reports, and ELN entries to support timelines
• Drive and improve workflows: documentation standardization and data digitization

Skills

Analytical method development

Method transfer

Troubleshooting

Data interpretation

Communication

Education

Bachelor's degree in chemistry/biochemistry/biology/chemical engineering or related field

Tools

HPLC

LC-MS

UV spectroscopy

Empower

Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer III to join our Preclinical Manufacturing & Process Development (PMPD) organization's Synthetic and Bioconjugation Scale-up Technologies (SBST) Analytics group, on-site in Tarrytown, NY. In this role, you will serve as the analytical lead to develop fit-for-purpose analytical methods, transfer methods, and provide troubleshooting support to advance a diverse bioconjugate pipeline.

This position offers the opportunity to lead and implement analytical deliverables, working closely with bioconjugation teams and internal/external collaborators (CDMOs) to advance bioconjugate programs from development to commercialization.

When & Where

• Shift Requirements: Full-time, standard business hours
• Location: On-site in Tarrytown, NY
• Flexibility & travel: Minimal to no travel; on-site presence required to support lab operations and collaboration with internal/external CDMO partners

What you'll do:

• Independently design and execute analytical testing, method development, and characterization to enable bioconjugate process development
• Serve as the subject matter expert to lead and design analytical deliverables: robust method development, method transfer to internal/external receiving labs, training, and troubleshooting to move programs forward
• Connect, interpret, and communicate complex results into clear, actionable next steps for technical and non-technical audiences to drive timely decisions
• Author high-quality documentation (e.g., procedures, development and characterization reports, ELN entries) in a timely manner to support program timelines
• Drive, build, and improve business workflows: documentation standardization, data digitization, and sample management
• Maintain compliance with lab and environmental safety requirements and promote a safe lab environment
• Proactively scout, evaluate, and implement new or improved technologies for high-throughput analytics and real-time decision-making
• Lead equipment upkeep and troubleshooting, maintain an organized workspace, and proactively plan for lab resources
• Mentor and support peers and junior team members (direct and/or indirect via matrix)

The environment and physical rhythms of this role:

• This is a hands-on, on-site laboratory role serving as analytical lead across bioconjugate programs, requiring close collaboration with internal teams and external CDMO partners and comfort navigating complex, ambiguous problems.
• Flexibility to thrive in a fast-paced, highly collaborative environment while independently driving projects forward is required.

Let's find out if we're a fit:

Must-haves:

• B.S. with 10+ years of relevant experience, M.S. with 7+ years, or recent Ph.D. with 0-3 years of relevant experience in chemistry, biochemistry, biology, chemical engineering, or a related field
• Hands-on experience with analytical method development for antibody, bioconjugate, and/or synthetic molecules (e.g., small molecule, PEG, peptides, and/or siRNA), such as electrophoresis, HPLCs, LC-MS, UV spectroscopy, plus associated software (e.g., Empower)
• Hands-on experience transferring methods to internal/external labs, and troubleshooting
• Demonstrated experience serving as an analytical lead for bioconjugate programs, collaborating effectively with internal teams and external CDMOs
• Strong written and verbal communication skills, including the ability to present data clearly to diverse audiences
• Experience drafting analytical methods, development, and characterization reports to support regulatory filing
• Ability to work independently and collaboratively across cross-functional teams to persuade and drive data-based decisions
• Demonstrated initiative, learning agility, and a growth mindset in a fast-paced environment

Preferred / nice-to-haves:

• Customer-centric mindset in providing analytical support across different phases of drug development
• Experience simplifying complex technical messages for varied audiences

Thrive today. Grow tomorrow.

• Student Loan Paydown program & Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well-Being programs (including physical & mental health)

#pmpd

Salary Range (annually):

$109,900.00 - $179,300.00

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.