Process Development Engineer I, Bioreactor Scale-Up & Development

Regeneron Pharmaceuticals, Inc.; Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Benefits offered by this job

Annual bonuses

Equity awards

401(k) company match

Health and wellness programs

Paid time off

Family support benefits

Job summary

Regeneron Pharmaceuticals, Inc. seeks a Process Development Engineer to advance bioreactor scale-up within PMPD. You will develop commercially viable processes, analyze data, and apply AI/ML to improve efficiency across bench to pilot scales.

The role is on-site in Tarrytown, NY, requiring a degree in chemical/biomedical engineering and hands-on experience with mammalian cell culture. Collaboration with cross-functional teams is essential.

Qualifications

• Bachelor’s or Master’s degree in Chemical Engineering, Biomedical Engineering, or a related field.
• Initiative to complete bold tasks and learn new technologies.
• Work independently and within a team on multiple projects simultaneously.
• Strong communication skills, including analytical, computer, and technical writing skills.

Responsibilities

• Cultivate mammalian cells producing biologics in bench and pilot-scale bioreactors.
• Prepare, sterilize, and operate bioreactors, buffers, and feeds, and maintain laboratory equipment.
• Analyze seed train, production, and quality data to advance process understanding and technology transfer.
• Author development reports, process transmittals, and electronic notebook documentation.
• Design and conduct experiments, including DOEs, to verify empirical and mechanistic models.
• Support scale-up of commercially enabling processes from bench to pilot and manufacturing scales.
• Lead and support data science projects, using AI/ML where appropriate, to optimize scale-up and comparability across scales.
• Partner with process development engineers on scale-dependent parameter characterization.

Skills

Bioreactor ops

DOE design

Data analysis

AI/ML

Communication

Education

Chemical/Bioengineering degree

Job description

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer to join our Bioreactor and Scale-Up Development Group within Preclinical Manufacturing and Process Development (PMPD), supporting our late-stage biologics pipeline in an on-site capacity. In this role, you will develop commercially viable manufacturing processes through pilot-scale studies and apply computational and data-analysis tools to improve process efficiency while collaborating with process development engineers and cross-functional development teams.

Location: Tarrytown, NY
Work model: On-site

Discover your role:

• Cultivate mammalian cells producing biologics in bench and pilot-scale bioreactors
• Prepare, sterilize, and operate bioreactors, buffers, and feeds, and maintain laboratory equipment
• Analyze seed train, production, and quality data to advance process understanding and technology transfer
• Author development reports, process transmittals, and electronic notebook documentation
• Design and conduct experiments, including DOEs, to verify empirical and mechanistic models
• Support scale-up of commercially enabling processes from bench to pilot and manufacturing scales
• Lead and support data science projects, using AI/ML where appropriate, to optimize scale-up and comparability across scales
• Partner with process development engineers on scale-dependent parameter characterization

This role requires:

• Bachelor’s or Master's degree in Chemical Engineering, Biomedical Engineering, or a related field with 0-2 years of experience
• Initiative and strive to complete bold tasks and learn new technologies
• Work independently and within a team on multiple projects simultaneously
• Strong communication skills, including analytical, computer, and technical writing skills

Preferred:

• knowledge of or interest in bioreactor operations, scale-up, and mammalian cell culture
• knowledge of or interest in data analytics and programming

Resources

YouTube Video on PMPD Bioreactor Scale-Up & Development: https://www.youtube.com/watch?v=uikD5fzEwyM&list=PL_7lj13Lp4fH4OssUue8J5bby6muZsaR4&index=8

YouTube Video on Career Development at Regeneron: https://www.youtube.com/watch?v=4fg18hC-gsw&list=PL_7lj13Lp4fH4OssUue8J5bby6muZsaR4&index=2

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits

For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/ . For other locations, additional information will be provided during the recruitment process.

Salary Range (annually) $80,300.00 - $131,100.00

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.