Process Development Associate Scientist

Amgen; United States; On-site; USD 90,000 - 120,000; Full time

Job summary

Amgen seeks a Process Development Associate Scientist to advance cell culture and purification processes for our late-stage pipeline. You will develop mammalian culture and purification steps, evaluate process robustness, transfer to manufacturing, and document results to support regulatory filings.

Basic qualifications include a Master’s degree or a Bachelor’s with 3 years in process development. Preferred: hands-on lab experience in cell culture or protein purification, strong attention to

Qualifications

• Master’s degree or Bachelor’s with 3 years in Process Development.
• Hands-on lab experience in cell culture or protein purification is preferred.
• Experience with Design of Experiments and statistical analysis is a plus.
• Strong oral and written communication skills.
• Self-motivated with strong organization and collaboration abilities.

Responsibilities

• Develop cell culture and purification manufacturing processes for Amgen's late-stage pipeline.
• Characterize process robustness and transfer processes to manufacturing.
• Contribute to drug substance process development in a team environment.
• Execute mammalian cell culture experiments at various scales (shake flasks to bioreactors).
• Perform purification experiments (filtration and chromatography) at bench and pilot scale as needed.
• Document data in lab notebooks and present results to the team.

Skills

Cell culture

Protein purification

Design of Experiments

Statistics

Communication

Organization

Interpersonal skills

Education

Master's degree or Bachelor's with 3 years Process Development experience

Job description

Process Development Associate Scientist

Join Amgen's Mission of Serving Patients. At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What we expect of you

• Develop cell culture and purification manufacturing processes for Amgen's late-stage pipeline.
• Scope of work includes developing cell culture and purification processes for recombinant proteins to improve the production yields, evaluating process robustness through process characterization, transferring processes to manufacturing, and conducting other relevant experiments such as facility fit and raw material evaluation.
• Work in a team environment to contribute to drug substance process development.
• Execute mammalian cell culture experiments at different scales in shake flasks and bioreactors.
• Execute purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed.
• Document experimental data in lab notebooks.
• Analyze the data and present to the team.
• Author technical reports and support regulatory filing as needed.
• Contribute to technology development projects to seek continuous improvement in reliability and efficiency.

Basic Qualifications:

Master's degree 1 OR Bachelor's degree and 3 years of Process Development experience

Preferred Qualifications:

• Relevant hands-on lab experience in cell culture or protein purification.
• Attention to details and critical thinking ability.
• Experience in Design of Experiments and statistical analysis is a plus.
• Strong oral and written communication skills.
• Self-motivated and strong organization skills.
• Strong interpersonal skills, and the ability to work in a dynamic and collaborative environment.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

Equal Opportunity Employer

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion,