Principle, Enterprise Architect

RXinsider LTD.

Temecula (CA)

On-site

USD 180,000 - 250,000

Full time

7 days ago
Be an early applicant

Get more replies from employers

Send a job-specific resume in minutes.

Job summary

RXinsider LTD. in Temecula, CA, is seeking a Principal Enterprise Architect to shape the enterprise architecture vision, strategy, and investment direction.

This senior technology leader partners with CIO and executives to align cloud, AI, cybersecurity, integration, and digital workplace platforms with patient safety and regulatory requirements. You will balance innovation with reliability, lead architecture governance, and guide technology investments across healthcare, pharmacy, and

Qualifications

  • 10+ years in enterprise or senior architecture roles
  • 5+ years leadership/advisory or portfolio-level decision environments
  • Experience influencing executives and aligning stakeholders
  • Healthcare or regulated environments experience
  • HIPAA, PHI protection, risk-based compliance understanding
  • Enterprise app, data, cloud, and infra architecture knowledge
  • Public cloud platforms (Azure, AWS, GCP)
  • AI/ML concepts in enterprise use cases
  • APIs and interoperability frameworks
  • Cybersecurity architecture and identity management familiarity

Responsibilities

  • Define and steward the enterprise architecture vision, principles, and standards
  • Translate business/healthcare strategy into actionable technology roadmaps
  • Lead architectural governance for alignment, consistency, and risk management
  • Advise executive leadership on technology investments and modernization
  • Provide strategic oversight for cloud-first and hybrid architectures
  • Guide adoption of AI and analytics to improve efficiency and outcomes
  • Define integration/interoperability strategy across platforms
  • Maintain security-by-design and zero-trust across architectures
  • Support digital workplace initiatives for clinician and workforce experience
  • Align architecture decisions with financial discipline and portfolio priorities

Job description

Position Summary

The Principal Enterprise Architect is a senior technology leader responsible for shaping and governing the organization’s enterprise architecture vision, strategy, and investment direction. Reporting to the Chief Information Officer, this role ensures that cloud, AI, cybersecurity, integration, and digital workplace platformsenable safe, compliant, and scalable business operations while accelerating digital transformation.

This leader balances innovation with reliability, serving as a trusted advisor to executives and clinical, business, and technology stakeholders. The Enterprise Architect ensures technology decisions protect patient data, support regulatory obligations, and deliver long‑term business value.

Essential Functions and Duties
Enterprise Strategy & Architecture Leadership
  • Define and stewardship the enterprise architecture vision, principles, and standards
  • Translate business and healthcare strategy into clear, actionable technology roadmaps
  • Lead architectural governance to ensure alignment, consistency, and risk management
  • Advise executive leadership on technology investment, modernization, and trade‑offs
Digital, Cloud & AI Enablement
  • Provide strategic oversight forcloud‑first and hybrid architecturessupporting mission‑critical systems
  • Guide responsible adoption ofAI and advanced analyticsto improve efficiency, insight, and outcomes
  • Champion modern architecture patterns that improve agility, scalability, and resilience
  • Evaluate emerging technologies with a disciplined focus on safety, reliability, and value realization
Integration, Interoperability & Digital Experience
  • Define enterpriseintegration and interoperability strategyacross pharmacy, operational, and business platforms
  • Enable seamless, secure data flow using APIs, middleware, and integration platforms
  • Drive simplification and rationalization of the application and data landscape
  • Support a secure, moderndigital workplacethat enhances clinician and workforce experience
Cybersecurity, Privacy & Risk
  • Embedsecurity‑by‑design and zero‑trust principlesacross all enterprise architectures
  • Ensure protection of PHI and compliance with HIPAA and healthcare security standards
  • Partner with security, compliance, and risk leaders to proactively mitigate enterprise risk
Financial & Portfolio Stewardship
  • Align architecture decisions with financial discipline and portfolio priorities
  • Support capital planning, investment governance, and value‑based decision‑making
  • Ensure technology investments deliver sustainable operational and clinical value
Experience & Profile
Leadership Background
  • 10+ years in enterprise or senior architecture roles
  • 5+ years operating in leadership, advisory, or portfolio‑level decision environments
  • Proven success influencing executives and aligning diverse stakeholders
Healthcare & Regulatory Experience
  • Experience operating in regulated healthcare or similarly complex environments
  • Strong understanding of HIPAA, PHI protection, and risk‑based compliance
Technical Depth
  • Enterprise application, data, cloud, and infrastructure architecture
  • Public cloud platforms (Azure, AWS, GCP)
  • AI/ML concepts and applied enterprise use cases
  • Integration platforms, APIs, and interoperability frameworks
  • Cybersecurity architecture and identity management
Preferred
  • HITRUST or comparable healthcare security frameworks
  • Experience with connected devices, IoT, or advanced digital platforms
Executive Competencies:
  • Strategic, systems‑level thinking
  • Executive communication and influence
  • Sound judgment and decision‑making under complexity
  • Change leadership and enterprise mindset
  • Outcome‑driven, disciplined, and collaborative
Why This Role Matters

This position directly shapes how technology enablespatient safety, regulatory trust, operational excellence, and digital growth. It is a high‑impact role for a leader who canbridge strategy and executionwhile modernizing specialty pharmacy and pharmaceutical distribution technology platforms responsibly.

Physical requirements

Vision, hearing, speech, movements requiring the use of wrists, hands and/or fingers. Must have the ability to view a computer screen for prolonged periods and the ability to sit for extended periods. Must have the ability to work the hours and days required to complete the essential functions of the position, as scheduled. Must have the ability to lift and maneuver items of at least 20 lbs. Must have the ability to travel occasionally. Working condition include normal office setting.

Mental Demands

Learning, thinking, concentration and the ability to work under pressure, particularly during busy times. Must be able to pay close attention to detail and be able to work as a member of a team to ensure excellent customer service. Must have the ability to interact effectively with co-workers and customers, and exercise self-control and diplomacy in customer and employee relations’ situations. Must have the ability to exercise discretion as well as appropriate judgments when necessary. Must be proactive in finding solutions.

Direct Reports

Yes or No

EEO Statement

FFF Enterprises and Nufactor are an equal opportunity employer and prohibits discrimination and harassment based on the following characteristics: race, color, religion, national origin, physical or mental disability, gender, age (40 years and over) qualified veteran and any other characteristic protected by state or federal anti-discrimination law covering employment. These categories are defined according to Government Code section 12920. The Company prohibits unlawful discrimination based on the perception that anyone has any of those characteristics or is associated with a person who has or is perceived as having any of those characteristics.

Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Director, Enterprise & Solutions Architect
Director, Enterprise & Solutions Architect

GoHealth Urgent Care • United States

On-site
USD 180,000 - 240,000
Principal Solutions Architect - Healthcare Pharmacy (Remote)
Principal Solutions Architect - Healthcare Pharmacy (Remote)

CareFirst BlueCross BlueShield • Baltimore (MD)

On-site
USD 155,000 - 279,000
Comprehensive benefits package
401k contribution programs
Various incentive programs
Senior Engineer, Full-Stack
Senior Engineer, Full-Stack

RXinsider LTD. • Temecula (CA)

Hybrid
USD 120,000 - 190,000
Principal Architect – PBM Modernization & AI Engineering
Principal Architect – PBM Modernization & AI Engineering

Worky • Dallas (TX)

Hybrid
USD 150,000 - 205,000
Enterprise Architect (REMOTE)
Enterprise Architect (REMOTE)

IHA • Livonia (MI)

On-site
USD 140,000 - 180,000
Senior Architect - Data & Semantic Intelligence
Senior Architect - Data & Semantic Intelligence

RXinsider LTD. • Northern (KY)

Hybrid
USD 171,000 - 209,000
Senior Principal Enterprise Architect
Senior Principal Enterprise Architect

Penn Medicine, University of Pennsylvania Health System • Philadelphia

Hybrid
USD 170,000 - 230,000
Enterprise Technology Architect Senior
Enterprise Technology Architect Senior

Arkansas Blue Cross Blue Shield • Little Rock (AR)

On-site
USD 140,000 - 190,000
Enterprise Architect (JR228652)
Enterprise Architect (JR228652)

ViziRecruiter,LLC. • City of Yonkers (NY)

On-site
USD 120,000 - 160,000
Senior Enterprise Architect
Senior Enterprise Architect

PCI Pharma Services • Rockford (IL)

On-site
USD 120,000 - 160,000