Principal Validation Engineer

Pfizer Inc.; North Andover (MA); Hybrid; USD 124,000 - 207,000; Full time

Benefits offered by this job

Bonus target 17.5%

Comprehensive benefits

401(k) with company match

Job summary

Pfizer Inc. in Andover, MA seeks a Principal Validation Engineer to own the site validation program and master plan. You will partner with Pfizer global and local teams to ensure compliance and drive lifecycle improvements across biologics manufacturing.

You will lead validation planning for large projects, manage governance, and coordinate with cross-functional stakeholders to maintain program health in a hybrid work environment.

Qualifications

• BA/BS in Science or Engineering with 6+ years experience or MBA/MS with 5+ years of experience or PhD/JD with 1+ year of experience or MD/DVM with any years of relevant experience.
• Experience in pharmaceutical, biopharmaceutical or biotechnology industry.
• Experience or broad knowledge in biopharmaceutical development, manufacturing, and lifecycle management.
• Experience in project management and leading complex projects.
• Effective written and verbal communication skills.
• Strong interpersonal skills and the ability to work collaboratively in a team environment across various business functions.

Responsibilities

• Establish and maintain overall Andover site validation philosophy and master plan in partnership with local validation program owners, technical subject matter experts, and relevant Pfizer global/network/site quality system principals applicable to biologics drug substance/drug substance intermediate production, testing, storage, and transport
• Operate PMO for Validation Program Lifecycle Projects
• Establish and maintain site governances necessary to interpret validation philosophies and polices, implement and improve uniform validation practices and approaches, as well as to measure and maintain site validation program health
• Maintain STS departmental infrastructure, and provide planning support for third party services utilized in validation and other technical services; oversee third party service provider service level and quality of service
• Program owner and expert for select technical/validation disciplines
• STS capital project portfolio and expense planning
• Lead site validation planning and management of validation activities for large capital or complex asset lifecycle projects

Skills

Project management

Biopharma experience

Communication skills

Cross-functional collaboration

Leadership

Education

BA/BS in Science or Engineering

MBA/MS

PhD/JD

MD/DVM

Job description

Use Your Power for Purpose

The Principal Validation Engineer under Andover Site Technical Services (STS) is the principal owner of the Pfizer (PGS) Andover site validation program and master plan. The incumbent is responsible for delivering overall site validation program effectiveness and compliance in partnership with validation program owners across Andover site functions and the Pfizer network

What You Will Achieve

• Establish and maintain overall Andover site validation philosophy and master plan in partnership with local validation program owners, technical subject matter experts, and relevant Pfizer global/network/site quality system principals applicable to biologics drug substance/drug substance intermediate production, testing, storage, and transport
• Operate PMO for Validation Program Lifecycle Projects
• Establish and maintain site governances necessary to interpret validation philosophies and polices, implement and improve uniform validation practices and approaches, as well as to measure and maintain site validation program health
• Maintain STS departmental infrastructure, and provide planning support for third party services utilized in validation and other technical services; oversee third party service provider service level and quality of service
• Program owner and expert for select technical/validation disciplines
• STS capital project portfolio and expense planning
• Lead site validation planning and management of validation activities for large capital or complex asset lifecycle projects

Here Is What You Need (Minimum Requirements)

• BA/BS degree in Science or Engineering with 6+ years of experience or MBA/MS with 5+ years of experience or PhD/JD with 1+ year of experience or MD/DVM with any years of relevant experience
• Experience in pharmaceutical, biopharmaceutical or biotechnology industry
• Experience or broad knowledge in biopharmaceutical development, manufacturing, and lifecycle management
• Experience in project management and leading complex projects
• Effective written and verbal communication skills
• Strong interpersonal skills and the ability to work collaboratively in a team environment across various business functions

Bonus Points If You Have (Preferred Requirements)

• Experience developing philosophies/approaches for or managing validation programs applicable to the manufacture of biopharmaceutical drug substance, drug product, or medical device
• Active participation in industrial/professional organization focused on advancing biopharmaceutical development, manufacturing, regulatory practices
• Demonstrated ability to lead or build teams for complex technical projects involving risk management
• Demonstrated leadership in a matrix organization

Physical / Mental requirements

• Ability to perform mathematical calculations, scientific computation, complex data analysis, verbal communication, written communication

Non-Standard work schedule, travel or environment requirements

• Occasional domestic and international travels
• Occasional off-hour support to address time-sensitive production and business-related issues

Other job details

Last day to apply: July 17th, 2026

Work Location Assignment: Hybrid

The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program.

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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Engineering