Principal Technologist or Associate Scientist, Assay Development

Zealand Pharma; Boston, Northern (MA, KY); Hybrid; USD 120,000 - 170,000; Full time

Job summary

Zealand Pharma in Boston, MA is seeking a Laboratory-based Principal Technologist or Associate Scientist, Assay Development to develop and qualify cell-based and binding immunogenicity assays and support biomarker and ligand binding efforts.

You will contribute to technology transfer to CROs, produce and characterize critical reagents, maintain cell cultures, analyze data, and document methods thoroughly in a collaborative, English-speaking team.

Qualifications

• Hands-on bioanalytical work and assay development experience.
• Experience with immunogenicity assays and quantitative ligand binding assays.
• Strong documentation and data-analysis skills.

Responsibilities

• Develop and qualify cell-based and ligand-binding immunogenicity assays.
• Support assay transfer and validation to CROs.
• Produce and characterize reagents for assay pipelines.
• Maintain cell cultures and analyze data with thorough documentation.

Skills

Bioanalytical techniques

Immunogenicity assays

Ligand binding assays

ELISA

Electrochemiluminescence

Affinity chromatography

Surface plasmon resonance

Data analysis

Documentation

English communication

Education

Biomedical laboratory technology or scientific degree (biology/biochemistry/pharmacy)

Tools

ELISA

Electrochemiluminescence

SPR

Job description

Principal Technologist or Associate Scientist, Assay Development page is loaded## Principal Technologist or Associate Scientist, Assay Developmentlocations: Sydmarken 11time type: Full timeposted on: Posted 2 Days Agojob requisition id: JR389**Principal Technologist or Associate Scientist, Assay Development****Your new position**We are seeking a Laboratory-based Principal Technologist, or a scientist with an interest in lab work, to join the Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences. In this role, you will play a key part in developing and qualifying high-quality assays to detect our novel peptide therapeutics and characterize immunogenicity during preclinical and clinical development. You will support the development of various assays, contribute to technology transfer to contract research organizations (CROs), and generate critical reagents essential to our assay pipeline.*We offer exciting responsibilities*:- Development and qualification of cell-based and ligand bindingimmunogenicity assays (anti-drug antibodies and neutralizing antibodies)- Support general ligand binding assay development, qualification, andsample analysis as required- Production, purification, and characterization of critical reagents- Cell culture maintenance and optimization for assay purposes- Support assay transfer and validation to contract research organizations(CROs)- Data analysis, interpretation, and comprehensive documentation**Your profile**We are looking for a dedicated and detail-oriented Laboratory-based Principal Technologist or a Scientist, with a genuine interest in lab work, a passion for assay development and analytical method science. You bring hands-on expertise in bioanalytical techniques and a strong understanding of how biomolecules behave in various analytical systems. You are a recognized technical contributor, highly motivated, and possess strong communication skills in English. You thrive in a collaborative environment and take pride in creating comprehensive documentation of your work.- Laboratory technologist qualification (e.g., biomedical laboratorytechnology) or a scientific degree (e.g., biology, biochemistry, pharmacy)with a clear interest in hands-on laboratory work- 5 to 10 years of hands-on experience in development and qualification ofassays including immunogenicity assays, biomarker assays, andquantitative ligand binding assays (cell-based and ligand binding formats)- Good understanding of various analytical techniques used forbiomolecules (e.g., ELISA, electrochemiluminescence, affinitychromatography, surface plasmon resonance, or related methods)- Thorough understanding of analytical methods for quantifying, detecting,and characterizing drug-induced immunogenicity- Excellent documentation and data analysis skills- Proven ability to master core processes independently while being aneffective team collaborator- Proficient in English, both written and oral communication**Your new team**The Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences - a dedicated group of specialists collaborating to understand the behavior of our drug candidates on efficacy and safety. You will work alongside experienced scientists and technologists committed to advancing high-quality bioanalytical support for our pipeline.**Let's bond and be bold**We have a unique culture, characterized by excellent teamwork and strong engagement across the organization. And we want you to help us strengthen this culture.Making bonds is at the core of everything we do. From discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other. We bond through curiosity and playfulness as a team, allowing ourselves to challenge common thinking and drive future innovation. Join us and let's bond and be bold.**October 18**, 2026, or as soon as possible. The applications will be reviewed as they come in. While a cover letter is not required, please include a few sentences in your CV explaining your motivation for applying.For further information, please contact **Vice President, Pharmacokinetics, Immunogenicity & Bioanalytical Sciences, Carsten Boye Knudsen, [e-mail] / 50603614.**We are committed to an inclusive recruitment process and welcome applications from all job applicants.**About Zealand Pharma A/S**Zealand Pharma A/S (Nasdaq: ZEAL) is a biotechnology company focused on advancing medicines for obesity and metabolic health. Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. To date, more than ten Zealand Pharma-invented drug candidates have entered clinical development, of which two products have reached the market and three candidates are in late-stage development. The Company has collaborations with global pharmaceutical and biotechnology partners for research, development, and commercialization. Founded in 1998, Zealand Pharma is headquartered in Copenhagen, Denmark, with a U.S. presence in Boston, Massachusetts. Learn more at www.zealandpharma.com.#LI-Onsite