Principal Scientist, Translational Immunology & Antibody Discovery Innovation

1596 MRL San Francisco, LLC; South San Francisco (CA); Vor Ort; USD 176.000 - 277.000; Vollzeit

Zusammenfassung

MSD is seeking a Principal Scientist for the South San Francisco Discovery Biologics group. The role focuses on adaptive immunity and B cell biology to advance immunization-based antibody discovery programs. You will lead multi-disciplinary teams, drive vaccine discovery initiatives, and contribute to strategic science across the organization.

The candidate will require a Ph.D. with 8+ years of relevant experience, a track record of therapeutic vaccine discovery leadership, and an ability to

Qualifikationen

• PhD with 8+ years in biophysics, biochemistry, structural biology or related discipline and relevant industry experience.
• Experience driving scientific and platform innovations in vaccine discovery and development.
• Experience leading therapeutic vaccine discovery programs.

Aufgaben

• Propose and lead technology development initiatives for immunization based de novo antibody discovery to increase candidate hit quality and decrease timelines.
• Lead and participate in cross-functional discovery project teams in partnership with therapeutic area scientists.
• Foster a high-performance growth mindset culture of collaboration, engagement, self-accountability, and inclusion.
• Stay abreast of external advancements in relevant scientific and technology fields.
• Promote the external reputation of our company’s Discovery Biologics department.

Kenntnisse

Antibody Therapeutics

B Cells

Biologics

Group Leadership

Immunology

Innovation

People Leadership

Program Leadership

Vaccine Development

Vaccine Research

Ausbildung

PhD in biophysics/biochemistry/structural biology or related field

Jobbeschreibung

Job Description We are on a quest for cures and are committed to be the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines. We are seeking an exceptional and experienced scientist in the role of Principal Scientist in the South San Francisco Discovery Biologics group. The qualified candidate will be a scientist with a breadth and depth of expertise in adaptive immunity and B cell biology to contribute to defining the future state of immunization-based antibody discovery capabilities. They will work closely with other team members and groups throughout the organization to help manage, perform, and troubleshoot antibody discovery programs. We recognize that the diversity in our team is our strength, and we are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a diverse group of researchers to drive our core mission.

What you will do:

• Propose and lead technology development initiatives for immunization based de novo antibody discovery to increase candidate hit quality and decrease timelines.
• Lead and participate in cross-functional discovery project teams in partnership with therapeutic area scientists.
• Foster a high-performance growth mindset culture of collaboration, engagement, self-accountability, and inclusion.
• Stay abreast of external advancements in relevant scientific and technology fields.
• Promote the external reputation of our company’s Discovery Biologics department.

What you will need to be successful in this role:

Education:

• Ph.D. (with 8+ years) in biophysics, biochemistry, structural biology or related science discipline and relevant industry experience

Required Experience and Skills:

• Expertise in vaccine discovery and therapeutic development
• Depth of knowledge in adaptive immunity and B-cell biology
• Track record of driving scientific and platform innovations in vaccine discovery and development
• Experience leading therapeutic vaccine discovery programs
• Established external reputation through publications, presentations, and/or scientific community engagement
• Excellent communication and collaboration skills
• Ability to manage multiple projects simultaneously

Preferred Experience and Skills:

• Experience utilizing AI/ML to support discovery strategy initiatives
• #EligibleforERP

Required Skills:

• Antibody Therapeutics
• B Cells
• Biologics
• Group Leadership
• Immune Response
• Immunology
• Innovation
• People Leadership
• Program Leadership
• Vaccine Development
• Vaccine Research

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

Compensation

Where required by law, the compensation range for this role is provided below. The salary range for the primary location of this role is: $176,200.00 - $277,300.00 This range reflects the Company's reasonable expectation of the base salary applicable to this role at the time of posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

Benefits

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

Location

The primary location for this posting is: USA - California - South San Francisco (Grand Ave)

Additional Locations

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance. Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.

Employment Details

Employee Status: Regular Relocation: Domestic/International VISA Sponsorship: Yes Travel Requirements: 10% Flexible Work Arrangements: Not Applicable Shift: 1st - Day Valid Driving License: No Hazardous Material(s): n/a

Our company is a global healthcare leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where we have codified our legacy for over a century. Our success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.