Principal Scientist, Surface Chemistry

F. Hoffmann-La Roche AG; Santa Clara (CA); Hybride; USD 120 000 - 189 000; Plein temps

Résumé du poste

F. Hoffmann-La Roche AG in Santa Clara is seeking a Principal Scientist to drive surface chemistry and material modifications for next-generation sequencing consumables.

You will design surface chemistries, develop assays to characterize biomolecule interactions, and help transfer processes from R&D to Ops in a multidisciplinary setting. The role requires a strong background in surface science and data-driven decision making, with emphasis on instrument use and software like JMP and Python for

Qualifications

• Background in surface science and device development.
• Experience with NGS-based applications is preferred.
• Ability to design surface modifications and characterize interactions.

Responsabilités

• Design and develop surface modifications and novel chemistries for consumables in NGS workflows.
• Characterize surface modifications and surface-biomolecule interactions in complex devices.
• Guide process transfer from R&D to Operations and support data analysis.
• Analyze datasets, author reports, and present recommendations to the team.

Connaissances

Surface science

Data interpretation

Biomolecule interactions

Formation

BS with 7+ years industrial experience

MS with 4+ years industrial experience

PhD with 3+ years industrial experience

Outils

JMP

Python

Description du poste

## Principal Scientist, Surface ChemistryApply: Santa Clara: Full time: Posted Today: End Date: November 2, 2026 (20 days left to apply): 202610-125205At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.### ### The PositionWe are seeking a talented scientist to join a team developing surface chemistries enabling NGS-based advanced applications and consumables. This position provides an exciting opportunity to work with outstanding scientists and engineers in a highly multidisciplinary environment. The successful candidate will have a broad background in surface science and device development. ### The Opportunity* You will design and develop surface modifications and novel chemistries and workflows enabling consumables for NGS applications.* You will develop assays and methods to characterize surface modifications and surface-biomolecule interactions in complex consumable devices.* You will drive the synthetic manipulation of material surfaces at a molecular level to precisely engineer surface energy characteristics and other properties that will ensure optimal device performance in a complex system.* You will use early stage instrumentation and SW and gain a deep understanding of the sequencing workflow and consumables.* You will design and execute studies to determine optimal process conditions for surface modifications, including sequencing data collection and data analysis.* You will support design and process transfer from R&D to Ops.* You will analyze complex data sets, author technical reports, and present findings and strategic recommendations to the team and the organization. ### Who You Are* You have a BS degree with 7+ years of industrial experience, MS with 4+ years of industrial experience, or PhD degree with 3+ years of industrial experience in Chemistry or a closely related field, with a focus on surface science and materials modification and development of surface modifications for biomolecule analysis.* Deep understanding of chemical principles governing interactions at biomolecule-device interfaces.* Proficiency in JMP and Python to interpret complex datasets and translate findings into actionable insights Behaviors, competencies, and qualities of the ideal applicant. * You have experience with NGS-based applications and/or platform development, including an understanding of the critical surface requirements* Understanding of principles and challenges of surface functionalization of microfluidic and lab-on-chip complex consumables.* Problem-solving and data-driven solutions, with aptitude for systematically analyzing issues within multidisciplinary systems* Experience with early stage instrumentationRelocation Benefits are not offered for this job posting. The expected salary range for this position based on California is 120,100- 188,650 USD annually. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.*Benefits* ### Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.