Principal Scientist, Stat. Programming- Early Oncology Development (Hybrid)

Scorpion Therapeutics; Pennsylvania; On-site; USD 140,000 - 210,000; Full time

Job summary

Scorpion Therapeutics is seeking an expert statistical programmer to support early development statisticians with exploratory and unplanned analyses in oncology programs. You will pre-process, transform, and analyze complex data to generate data sets, tables, and graphics for regulatory submissions.

This role demands leadership across projects, development of programming standards, and collaboration across global teams to ensure quality, timeliness, and cross-functional alignment with CDISC/ADaM

Qualifications

• Excellent interpersonal, written/oral/presentation skills; strong project management and leadership across multiple complex programs
• Significant expertise in SAS and clinical trial programming (data steps, procedures, SAS/MACRO, SAS/GRAPH)
• Experience setting strategy and developing statistical programming deliverables (datasets, analyses, report tables/graphics) meeting quality, compliance, and timeliness requirements
• Ability to design complex algorithms; implement statistical methods not available in commercial software
• Experience with large databases; CDISC and ADaM
• Quality/process compliance; strategic thinking; anticipate stakeholder requirements; work across cultures/geographies
• Preferred skills: Python and R

Responsibilities

• Provide technical consultation and analytical support to early development statisticians for exploratory and unplanned analyses
• Address operational challenges requiring strategic solutions across early oncology development
• Support development of programming standards to enable efficient, high-quality programming deliverables
• Facilitate global adoption of standards and programming best practices within early oncology
• Pre-process, filter, and manipulate complex data for molecular biomarker, imaging, and other external (non-traditional lab) data
• Lead and actively contribute to departmental strategic initiative project teams

Skills

SAS programming

Clinical trial programming

Data management

CDISC/ADaM

SAS Macro

Python and R

Interpersonal leadership

Project management

Education

BA/BS in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering or related field

MS in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering or related field

Job description

Primary Activities

• Provide technical consultation and analytical support to early development statisticians for exploratory and unplanned analyses
• Address operational challenges requiring strategic solutions across early oncology development
• Support development of programming standards to enable efficient, high-quality programming deliverables
• Facilitate global adoption of standards and programming best practices within early oncology
• Pre-process, filter, and manipulate complex data for molecular biomarker, imaging, and other external (non-traditional lab) data
• Lead and actively contribute to departmental strategic initiative project teams

Education and Minimum Requirement

• BA/BS in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering or related field + 12+ years SAS/R programming in a clinical trial environment; or
• MS in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering or related field + 10+ years SAS/R programming in a clinical trial environment

Department/Position Required Skills and Experience

• Excellent interpersonal, written/oral/presentation skills; strong project management and leadership across multiple complex programs
• Significant expertise in SAS and clinical trial programming (data steps, procedures, SAS/MACRO, SAS/GRAPH)
• Experience setting strategy and developing statistical programming deliverables (datasets, analyses, report tables/graphics) meeting quality, compliance, and timeliness requirements
• Ability to design complex algorithms; implement statistical methods not available in commercial software
• Experience with large databases; CDISC and ADaM
• Quality/process compliance; strategic thinking; anticipate stakeholder requirements; work across cultures/geographies

Preferred Skills

• Early oncology development; developing/implementing programming standards; SOPs/SDLC; Microsoft Project; regulatory submission leadership; PK/PD, process improvement methodologies; Python and R