Principal Scientist, Spatial Multiomics

Johnson & Johnson

Cambridge (MA)

On-site

USD 117,000 - 201,000

Full time

7 days ago
Be an early applicant
Application generator

Don’t send a generic resume — generate a resume and cover letter tailored to this exact role.

Get past ATS filters

Benefits offered by this job

401(k) plan
Long-term incentive program
Vacation 120 hours/year
Parental Leave 480 hours

Job summary

Johnson & Johnson is seeking a Principal Scientist in Cambridge MA or Spring House PA to lead development of advanced spatial omics and massively parallel functional genomics platforms. This role blends scientific leadership with hands-on experimental work to build integrated workflows that connect perturbation biology with single-cell and spatial readouts.

The successful candidate will guide platform deployment, collaborate with computational teams, and drive therapeutic discovery across

Qualifications

  • Minimum of 6 years of biotechnology or pharmaceutical industry experience, or equivalent translational research experience.
  • Demonstrated leadership with publications, presentations, patents, or major tech contributions.
  • Deep expertise in spatial omics or functional genomics with cross-domain experience.

Responsibilities

  • Lead development and deployment of massively parallel reporter assays and spatial omics workflows.
  • Design experimental workflows integrating perturbation, reporter assays, molecular profiling, and spatial analysis.
  • Evaluate and scale emerging technologies for pathway discovery and translational research.
  • Serve as SME in spatial biology and high-content genomics screening.

Skills

Spatial omics
Functional genomics
MPRA
CRISPR screens
Perturb-seq
Pooled screening
Team collaboration
Scientific communication

Education

PhD in Genetics/Genomics/Molecular Biology/Systems biology

Tools

Bruker CosMx
10x Genomics Visium
Xenium
Single cell & spatial analysis tools

Job description

Johnson & Johnson is seeking a Principal Scientist in Cambridge MA or Spring House PA to lead development of advanced spatial omics and massively parallel functional genomics platforms. This role blends scientific leadership with hands-on experimental work to build integrated workflows that connect perturbation biology with single-cell and spatial readouts.

The successful candidate will guide platform deployment, collaborate with computational teams, and drive therapeutic discovery across

Get your free, confidential resume review.
or drag and drop your file here.