Principal Scientist I, Process Chemistry & Scale-Up

Parexel; Denver (CO); On-site; USD 110,000 - 160,000; Full time

Benefits offered by this job

Full benefits

Sick time

401K

Paid holidays

Paid time off

Job summary

Parexel is seeking a Principal Scientist I to join the Chemical Engineering R&D effort on a Parexel FSP assignment, onsite at a client in Rahway, NJ. The role focuses on developing and optimizing chemical processes from lab to multi-kilogram scale, performing reactions, extractions, distillations, crystallizations, and drying, with rigorous documentation and GLP compliance.

The successful candidate will hold a PhD (or MS with 3+ years pharma experience) and collaborate across cross-functional

Qualifications

• PhD in Chemistry or related field; or MS with 3+ years pharma/biopharma experience.
• Experience with chemical process development, scale-up, and unit operations.
• Strong lab skills, safe handling, data generation and documentation per GLP.
• Knowledge of process robustness, quality, yield, and environmental considerations.
• Ability to work accurately in a fast-paced, regulated lab with minimal supervision.
• Proficiency with MS Office and data analysis tools.
• Strong communication and collaboration within cross-functional teams.
• Ability to follow established procedures to meet safety and quality requirements.
• Initiative to develop and improve lab systems and methods.

Responsibilities

• Develop and optimize chemical process steps spanning reactions, extractions, distillations, crystallizations, filtrations, drying.
• Work on lab-scale to multi-kilogram scale with documentation and reports.
• Plan, analyze, and document experiments; write clear reports.
• Work with a variety of chemicals and laboratory equipment.
• Collaborate with project teams to bring APIs through R&D.
• Ensure safety, GLP/GMP expectations.

Skills

Process development

Scale-up

Lab safety

Data analysis

GLP

MS Office

Teamwork

Procedure compliance

Independent work

Education

PhD in Chemistry

MS in Chemistry

Tools

Mettler Toledo EasyMax/Optimax

HPLC

GC

FTIR

Raman

PVM

KF

DSC

Aspen

MATLAB

Job description

Parexel is seeking a Principal Scientist I to join the Chemical Engineering R&D effort on a Parexel FSP assignment, onsite at a client in Rahway, NJ. The role focuses on developing and optimizing chemical processes from lab to multi-kilogram scale, performing reactions, extractions, distillations, crystallizations, and drying, with rigorous documentation and GLP compliance.

The successful candidate will hold a PhD (or MS with 3+ years pharma experience) and collaborate across cross-functional