Principal Scientist (Director), Clinical Research, Immunology

MSD; San Francisco (CA); Sur place; USD 256 000 - 403 000; Plein temps

Avantages offerts par ce poste

Medical, dental, vision benefits

Retirement benefits (401k)

Paid holidays

Vacation

Compassionate and sick days

Résumé du poste

MSD Malaysia is seeking a Clinical Director (Principal Scientist) to lead strategic planning and execution of late-stage clinical development for immunology projects. You will design trials, supervise clinical scientists, and partner with regulatory, statistics, and manufacturing teams to advance investigational drugs.

The role requires at least 5 years in clinical or development roles, with strong collaboration and a track record in phase 2/3 rheumatology studies.

Qualifications

• MD/DO/MD-PhD or DO-PhD required.
• Minimum of 5 years of clinical and/or development experience.
• Proven track record in design and execution of phase 2/3 trials in rheumatologic diseases is preferred.
• Strong interpersonal and cross-functional collaboration skills.

Responsabilités

• Evaluate pre-clinical and translational work to inform the early clinical development plan.
• Provide clinical development support for external opportunities to grow the Immunology Pipeline.
• Develop clinical development strategies and plan trials based on these strategies.
• Monitor ongoing or new clinical trials for investigational drugs.
• Analyze and summarize clinical findings to support safety, efficacy, and regulatory filings.
• Supervise Clinical Scientists in the execution of clinical studies.
• Collaborate with cross-functional teams (regulatory, statistics, manufacturing) and report progress to leadership.
• Author detailed development documents, budgets, and position papers for internal and external audiences.
• Travel about twenty percent of the time to manage projects.

Connaissances

Cross-functional teamwork

Rheumatology

Immunology

Clinical development

Clinical trial design

Clinical research

Formation

MD, DO, MD/PhD, or DO/PhD

Description du poste

The Clinical Director (Principal Scientist) has primary responsibility for the strategic planning and directing clinical research activities involving investigational compounds in Immunology. With a focus on late-stage development, the Clinical Director will manage the entire cycle of clinical development, including determination of appropriate disease indications to pursue and subsequent study design, initiation, execution, monitoring, analysis, regulatory filing, and publication.

Specific Responsibilities

• Evaluating pre-clinical and translational work for the purpose of generating the early clinical development plan and Investigational New Drug applications.
• Providing clinical development support of business development assessments of external opportunities to grow the Immunology Pipeline
• Developing clinical development strategies for investigational drugs and planning clinical trials (design, operational plans, settings) based on these clinical development strategies
• Monitoring and managing the conduct of ongoing or new clinical trials for investigational drugs
• Analyzing and summarizing the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication; and Participation in internal and joint internal/external research project teams relevant to the development of new compounds

Additional Responsibilities

• Supervise the activities of Clinical Scientists in the execution of clinical studies.
• Work closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects; and assist the Senior Director, Associate Vice-President/Vice-President and Product Development Team Lead in ensuring that appropriate corporate personnel is informed of the progress of studies of our company and competitors' drugs and internal and external expert opinion on scientific questions relevant to his/her areas of responsibility.

Professional Development

• Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies
• Identification of scientifically and operationally strong investigators who can assist in the development of our company's investigational drugs in Immunology
• Establishing collaborative relationships with external experts in Rheumatology diseases, particularly those whose research focus and expertise can inform and assist the evaluation of the company's investigational drugs
• Attending appropriate scientific meetings to maintain his or her competency and to maintain awareness of research activities in his/her area of responsibility.

To Accomplish These Goals

• Author detailed development documents, presentations, budgets, and position papers for internal and external audiences
• Facilitate collaborations with external researchers around the world
• Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.

Qualifications

• Education M.D., D.O., M.D./Ph.D, or D.O./Ph.D.
• Required education and experience Minimum of 5 years of clinical and/or development experience (academia, clinical medicine, and/or corporate clinical development).
• Demonstrated record of scientific scholarship and achievement
• Prior experience in design and execution of phase 2 or 3 clinical trials in rheumatologic diseases is preferred
• Strong interpersonal skills, as well as the ability to work collaboratively in a cross-functional team environment
• Required Skills: 교차 기능 팀워크, 류마티스학, 면역학, 임상 개발, 임상 시험 계획, 임상 연구

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.

As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds.

The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment.

We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

당사는 글로벌 헬스케어 리더로서 다양한 처방약, 백신 및 동물 건강 제품 포트폴리오를 가지고 있습니다. 잠재력과 성공 사이의 차이는 혁신과 창의력을 일깨우는 불꽃에 있습니다. 이는 백년이 넘는 세월 동안 우리가 유산으로 지켜온 신조입니다. 우리의 성공은 윤리적 성실성, 전향적인 모멘텀, 그리고 글로벌 헬스케어에서 새로운 이정표를 세우겠다는 고무적인 임무에 의해 가능해 집니다.

The salary range for this role is $255,800.00 - $402,700.00

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.

• medical, dental, vision healthcare and other insurance benefits (for employee and family)
• retirement benefits, including 401(k)
• paid holidays
• vacation
• compassionate and sick days

Employee Status: 정기

Relocation: Domestic

VISA Sponsorship: No

Travel Requirements: 25%

Flexible Work Arrangements: Hybrid

Shift: Not Indicated

Valid Driving License: No

Hazardous Material(s): n/a

Job Posting End Date: 10/8/2026

US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance