Principal Scientist, Biostatistics, Clinical Safety Statistics

Scorpion Therapeutics; North Wales (Montgomery County); Hybrid; USD 150,000 - 210,000; Full time

Job summary

Scorpion Therapeutics is seeking a Lead statistician to oversee safety analyses in Oncology programs as part of the CSS group, providing scientific expertise and strategic oversight for safety analyses throughout the product lifecycle.

You will partner with cross‑functional teams to design and interpret safety analyses, develop innovative statistical methods and tools for safety monitoring, and communicate findings to regulators and stakeholders.

Qualifications

• PhD or equivalent in statistics/biostatistics with 6+ years of relevant experience.
• Strong expertise in survival analysis, meta-analysis, Bayesian methods, and SAS/R.
• Knowledge of regulatory safety requirements, clinical trial design, and real-world data analysis.

Responsibilities

• Partner with cross-functional teams to design and interpret safety analyses.
• Develop innovative statistical methods and tools for safety monitoring.
• Communicate findings to stakeholders, including regulators.

Skills

Survival analysis

Meta-analysis

Bayesian methods

Statistical software (SAS/R)

Education

PhD in statistics/biostatistics

MS with 9+ years experience

Tools

SAS

R

Job description

Role:

Lead statistical safety evaluation within the CSS group for Oncology Therapeutic Area programs, providing scientific expertise and strategic oversight for safety data analyses throughout the product lifecycle.

Responsibilities:

• partner with cross-functional teams to design and interpret safety analyses;
• develop innovative statistical methods and tools for safety monitoring;
• communicate findings to stakeholders, including regulators.

Qualifications:

• PhD or equivalent in statistics, biostatistics, with 6+ years (or MS with 9+ years) of relevant experience;
• strong expertise in survival analysis, meta-analysis, Bayesian methods, and statistical software (SAS/R);
• knowledge of regulatory safety requirements, clinical trial design, and real-world data analysis.

Preferred:

• knowledge of drug development stages from preclinical to post-marketing, experience with AI tools, and understanding of disease biology.

High-Value:

• focus on oncology safety data, comprehensive safety analysis throughout product development, and collaboration with Risk Management Safety Teams.

Work setup:

hybrid in the US with approximately 10% travel.