Principal Safety Scientist — PV & Risk Leader

GlaxoSmithKline; Philadelphia (Philadelphia County); On-site; USD 140,000 - 220,000; Full time

Job summary

GlaxoSmithKline seeks a Medical/Scientific Safety professional to provide pharmacovigilance expertise in safety assessments for clinical development and post-marketing products.

The role includes leading signal detection, generating safety evaluations, and contributing to risk management plans with senior colleagues. Strong cross-functional collaboration and clear risk communication are essential.

Qualifications

• Degree in a health or life sciences discipline or healthcare professional qualification (e.g., PharmD, PhD, RN, RPh, BSc) or equivalent experience.
• Experience in pharmacovigilance, safety evaluation, clinical safety or a related role in pharma/biotech.
• Practical knowledge of safety evaluation methods, signal detection principles and adverse event reporting.
• Experience with clinical development and post-marketing safety activities.

Responsibilities

• Leads signal detection and evaluation for assigned products.
• Produces clear, accurate safety evaluations for internal/regulatory requests.
• Contributes to Risk Management Plans and safety documentation.
• Authors and reviews global periodic safety reports, aggregate reports, protocols.
• Participates in audit/inspection follow-up activities.
• Collaborates with SERM physicians to investigate safety issues.

Skills

Digital Fluency

Enterprise Leadership

Influencing Without Authority

Pharmacovigilance

Presentation Techniques

Education

Degree in health or life sciences

Advanced medical or scientific degree

Tools

Safety databases

Signal detection tools

Job description

GlaxoSmithKline seeks a Medical/Scientific Safety professional to provide pharmacovigilance expertise in safety assessments for clinical development and post-marketing products.

The role includes leading signal detection, generating safety evaluations, and contributing to risk management plans with senior colleagues. Strong cross-functional collaboration and clear risk communication are essential.