Principal Programmer - RWD/EPI

Cytel; Topeka (KS); Vor Ort; USD 120.000 - 170.000; Vollzeit

Zusammenfassung

Cytel Inc. is seeking an experienced epidemiology/RWE analyst to prepare Real World data, advise on analytic strategies, and support stakeholders across regulatory and research activities.

You will program and conduct statistical analyses, develop data standards, create visualizations and reporting for observational data, and collaborate with Medical Affairs and safety teams to support regulatory documents and clinical development plans.

Qualifikationen

• Master’s degree or PhD in epidemiology, biostatistics, statistics, bioinformatics or economics with 5+ years of RWE analytics experience
• Proficiency in SQL; SAS or R required
• Deep expertise analyzing RWE data sources such as Optum Clinformatics Datamart, Truveta and UK Biobank
• Familiarity with relational databases and claims data layouts
• Experience with applied statistics including regression, survival analysis, and propensity weighting
• Excellent project management and stakeholder communication skills

Aufgaben

• Assist in development of study protocols and analysis plans leveraging large RWD sources (Claims and/or EHR)
• Liaise with data vendors to obtain relevant data extracts
• Create analytical databases from data extracts to support analyses
• Conduct analyses per study protocols and analysis plans
• Produce tables/figures for discussions with investigators and clients
• Present results internally and to clients
• Assist in preparing study reports and deliverables
• May assume supervisory responsibilities in the future

Kenntnisse

SQL

SAS

R

Statistical analysis

Project management

Ausbildung

Master’s degree or PhD in epidemiology/biostatistics/statistics/bioinformatics/economics

Tools

Optum Clinformatics Datamart

Truveta

UK Biobank

Jobbeschreibung

You will contribute by:

• Providing support to the Epidemiology team by preparing Real World data, advising on data analytic strategies, and supporting stakeholders in various epidemiology analytic activities




• Programming and conducting statistical analysis under the direction and supervision of epidemiologists/statisticians including data coding, creation of algorithms, linkage of datasets, and use of statistical packages or platforms




• Supporting statistical programming to generate innovative means of data standardization, visualization, and reporting of observational data




• Supporting Medical Affairs (e.g. observational studies leveraging RWD); Global Patient Safety and Risk Management (e.g., analysis to obtain background rates) for the development of regulatory/safety documents, and Clinical Development (e.g.; assessment of patient populations/ protocol feasibility)




• The position will partner with Epidemiologists to manage relationships with internal and external stakeholders




• Being able to prioritize and manage work across multiple projects and stakeholders




• Providing strong communication to ensure successful and timely project delivery




• Solving technical problems with experience and expertise

Summary of Key Responsibilities:

• Assist in development of study protocols and analysis plans leveraging large RWD sources (Claims and/or EHR)




• Liaise with data vendors to obtain relevant data extracts for research studies consistent with study protocols




• Create analytical databases from data extracts to facilitate conduct of data analyses




• Conduct analyses consistent with methods set forth in study protocols and analysis plans




• Produce tables and figures for discussions with other investigators, clients, and for study reports




• Present results internally and to clients




• Assist in the preparation of study reports and other deliverables




• May have supervisory responsibilities in the future

What we’re looking for:

• Master’s degree or PhD in related field (epidemiology, biostatistics, statistics, bioinformatics, economics) and 5+ years of experience conducting RWE analytics for pharma industry, CRO, or academic institution




• Intermediate to expert level proficiency in SQL is a must. In addition, SAS or R proficiency is required




• Deep expertise analyzing RWE data sources such as Optum (Clinformatics Datamart® and Market Clarity), Truveta and UK Biobank. Experience analyzing clinical trial and/or registry data is desirable




• Familiarity with relational databases and proficient understanding of claims and ancillary file layouts




• Experience with applied statistics including regression analysis (OLS, longitudinal, logistic, Cox, GLM/GEE), surrogate analyses (Kaplan-Meier, cumulative incidence, accelerated failure time models), and propensity weighting




• Excellent project management skills; can prioritize multiple tasks and goals to ensure timely completion




• Confident and competent when interacting with internal and external stakeholders




• Strong written/verbal communication skills. Highly effective at summarizing and presenting key considerations and evidence

Cytel Inc. is an Equal Employment / Aff…? Applicants are considered for all positions without regard to race, color, religion, sex, national origin, age, veteran status, disability, sexual orientation, gender identity or expression, or any other characteristics protected by law.