Principal Programmer Analyst

GSK; Upper Providence (Delaware County); On-site; USD 120,000 - 190,000; Full time

Benefits offered by this job

hybrid working model

annual bonus based on company perfomm–

healthcare and wellbeing programmes

pension plan membership

shares and savings programme

Job summary

GSK is seeking a Principal Programmer Analyst to join our Clinical Programming team. You will lead study delivery in an agile, squad-based environment, mentor junior staff, and collaborate with cross-functional groups across clinical, statistical, and operational teams to bridge scientific requirements with technical solutions.

You will ensure high-quality outputs, contribute to regulatory interactions, and help drive the adoption of governance and best practices across the programming function.

Qualifications

• Bachelor’s degree in Mathematics, Computer Science, or a related discipline.
• Five+ years of programming experience with at least one language and ability to select appropriate tools for tasks.
• Three+ years in the pharmaceutical/biotech industry with understanding of clinical trials and therapeutic areas.

Responsibilities

• Independently lead programming activities for one or more studies, ensuring development, maintenance, and validation of complex analysis packages
• Foster quality assurance by adhering to Good Programming Practices and CDISC
• Mentor junior programmers with guidance on technical tasks and best practices
• Lead programming support for regulatory interactions (e.g., EMA, FDA)
• Identify gaps and implement innovative solutions aligned with standards
• Establish governance frameworks and manage risk with timely escalation

Skills

Leadership

Mentoring

Stakeholder communication

Governance

Agile

Problem solving

Education

Bachelor’s degree in Mathematics, Computer Science, or related discipline

Tools

R

Job description

Principal Programmer Analyst

We are seeking a Principal Programmer Analyst to join our Clinical Programming team, contributing to pipeline delivery across complex and pivotal studies. This role operates within an agile, squad-based environment, where you will lead study delivery, collaborate with cross-functional teams, and act as a technical mentor to ensure high-quality and timely outputs. Working closely with stakeholders across clinical, statistical, and operational functions, you will play a key role in bridging scientific requirements with technical solutions, supporting the successful execution of clinical development programmes within a global setting.

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included.

Key Responsibilities

• Independently lead programming activities for one or more studies, ensuring development, maintenance, and validation of complex analysis packages
• Foster quality assurance by ensuring programming activities adhere to standards such as Good Programming Practices and CDISC
• Mentor junior programmers by providing guidance and support in technical programming tasks and industry best practices
• Lead programming support for regulatory interactions (e.g., EMA, FDA)
• Identify gaps and inefficiencies and recommend and implement innovative solutions aligned with standards and best practices
• Establish and uphold governance frameworks, identify risks early and devise mitigation plans, ensuring timely escalation

Basic Qualifications

• Bachelor’s degree in Mathematics, Computer Science, or a related discipline
• Five or more years if experience with at least one programming language and ability to evaluate and select appropriate tools or languages for specific tasks
• Three or more years of experience working in the pharmaceutical/biotech industry with advanced understanding of clinical trials and therapeutic areas, applied to enhance programming outputs and decision-making
• Experience leading discussions on programming strategies, displays, and custom programs
• Experience implementing principles of governance, quality control, and compliance with regulatory requirements and programming standards

Preferred Qualifications

• Experience guiding others in the use of Artificial Intelligence/Machine Learning (AI/ML) tools or applying these tools to improve efficiency
• Experience contributing to internal technical discussions, forums, or external technical organizations
• Application of critical thinking to implement standards and collaborate with stakeholders where deviations are required
• Ability to articulate complex technical information effectively to both technical and non-technical stakeholders
• Experience contributing to department strategies and key technical initiatives through working groups or sub-teams
• Demonstrated networking and collaboration across departments, divisions, and external partners
• Experience facilitating integration across matrix teams and contributing to planning and execution of programming activities
• Experience guiding teams and individuals, fostering continuous improvement, collaboration, and innovation
• Demonstrated proficiency in R

Benefits

• competitive salary
• an annual bonus based on company performance
• healthcare and wellbeing programmes
• pension plan membership
• shares and savings programme
• hybrid working model

Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives.

GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We're uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D.

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We are a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive.

Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more on our career site.