Principal Investigator (MD/DO) Clinical Research -247365

Medix™; Minneapolis (MN); On-site; USD 180,000 - 250,000; Full time

Job summary

A clinical research organization seeks a Principal Investigator (MD/DO) to lead clinical trials in Minneapolis. The role includes overseeing trials, ensuring compliance with regulations, and building a new research site. Ideal candidates will have board certification in relevant specialties and prior experience in clinical research. This position provides a unique opportunity to impact patient access to innovative therapies and grow within an established multi-site organization.

Qualifications

• Board certification in Neurology, Psychiatry, Family Medicine, Internal Medicine, or Emergency Medicine.
• Active Minnesota medical license or eligibility to obtain one.
• Experience as a Principal Investigator in clinical trials.

Responsibilities

• Serve as Principal Investigator for clinical trials.
• Ensure compliance with clinical research regulations.
• Provide medical oversight for study participants.
• Perform protocol-required assessments and procedures.
• Review AEs/SAEs and safety data with timely reporting.
• Lead sub-investigators, coordinators and site staff.

Skills

Clinical trials oversight

Leadership

Communication

Regulatory compliance

Education

MD or DO with board certification

Active Minnesota medical license

Job description

Location: Minneapolis, Minnesota 55403

Employment Type: Direct Hire, W-2

Schedule: Full-Time, Monday – Friday, 9:00 AM – 5:00 PM

Specialties Preferred: Neurology, Psychiatry, Family Medicine, Internal Medicine, Emergency Medicine

About the Opportunity

Medix is partnered with a multi-site clinical research organization supporting industry-sponsored pharmaceutical clinical trials. This Principal Investigator (MD/DO) opportunity is ideal for an experienced physician who is interested in partnering to launch and grow a new clinical research site, while leveraging the operational infrastructure, sponsor relationships, and support of an established research organization.

This role offers a unique opportunity for a PI who enjoys hands-on clinical research, values high-quality patient care, and is motivated by the chance to help build a site from the ground up with long-term growth potential.

Overview

The Principal Investigator (MD/DO) serves as the medical and scientific lead for clinical trials conducted at the research site. The PI is responsible for ensuring subject safety, protocol compliance, data integrity, and regulatory adherence, while providing comprehensive medical oversight throughout the conduct of clinical studies.

Key Responsibilities

• Serve as the Principal Investigator of record for assigned industry-sponsored clinical trials
• Provide medical oversight and clinical decision-making for study participants, including management of comorbid conditions
• Ensure trials are conducted in compliance with ICH-GCP, FDA regulations, IRB requirements, and sponsor protocols
• Perform or supervise protocol-required clinical assessments and study procedures
• Review and assess adverse events (AEs), serious adverse events (SAEs), and safety data, ensuring timely and accurate reporting
• Lead and collaborate with sub-investigators, study coordinators, and site staff
• Participate in site initiation visits, monitoring visits, audits, and inspections
• Communicate effectively with sponsors, CROs, and regulatory authorities
• Maintain accurate and complete source documentation and regulatory files
• Contribute to the development, growth, and long-term success of a newly launched research site

Required Qualifications

• MD or DO with board certification (or eligibility) in Neurology, Psychiatry, Family Medicine, Internal Medicine, or Emergency Medicine
• Active, unrestricted Minnesota medical license, or eligibility to obtain
• Demonstrated experience serving as a Principal Investigator on industry-sponsored pharmaceutical clinical trials (required)
• Strong understanding of clinical research regulations, GCP, and FDA requirements
• Interest in partnering with an established clinical research organization to launch and build a new site from the ground up
• Excellent communication, leadership, and collaborative skills

Why This Role Is Unique

• Opportunity to help launch and shape a new clinical research site
• Backed by the infrastructure, operational support, and sponsor relationships of an established multi-site organization
• Ability to expand long-term involvement in clinical research and site leadership
• Meaningful impact on patient access to innovative therapies

Interested in learning more about this opportunity or exploring other Principal Investigator opportunities with Medix nationwide? Apply today to start the conversation.