Principal Developer - Next Generation Sequencing - Translational Research, Innovation & Test Development Office (TRITDO)

Mayo Foundation for Medical Education and Research; Rochester (MN); Hybrid; USD 85,000 - 128,000; Full time

Benefits offered by this job

Medical plans

Dental coverage

Vision plan

HSA/FSAs

Job summary

Mayo Clinic is seeking a division/departmental leader to guide test development and innovation across multiple projects in a high‑volume lab setting. The role requires expertise in modern laboratory methods, data interpretation, and cross‑disciplinary collaboration.

This senior position emphasizes independent initiative, project leadership, and the ability to apply scientific literature to implement novel laboratory technologies, while mentoring junior staff on diverse platforms.

Qualifications

• Bachelor's degree in clinical/medical laboratory science or related field with certification.
• Six years of lab experience or advanced degree with experience.
• Master's/PhD preferred in chemical/biological/clinical lab science.

Responsibilities

• Lead test development and innovation across multiple projects.
• Collaborate with Bioinformatics and IT to evaluate novel tech and methods.
• Mentor test development staff and drive cross‑department initiatives.

Skills

Independent work

Communication

Literature interpretation

Project management

Analytical thinking

NGS experience

Education

Bachelor's in CLS/MLS/MT/biological sciences

Master's or Doctoral degree in related field (preferred)

Tools

None

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

• Medical:Multiple plan options.
• Dental:Delta Dental or reimbursement account for flexible coverage.
• Vision:Affordable plan with national network.
• Pre-Tax Savings:HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Responsibilities

Division/Departmental test development/innovation platform leader who develops, innovates, evaluates, and implements novel/new tests, methodologies, technologies, or products for the laboratory under the intellectual and scientific guidance of laboratory directors and senior principal developer. Test development/innovation platform leader responsible for development/innovation support of multiple projects across the division/department. Responsible for improvement of existing methods or implementation of novel technology of proven validity. Test development/innovation platform leader on cross-departmental teams, including Bioinformatics and IT, to create final recommendations to the laboratory directors and supervisors in the evaluation of novel laboratory equipment, instrumentation, procedures, and computer software and hardware. Test development/innovation platform leader and mentor for test development /innovation staff.

**This position is not eligible for visa sponsorship. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program**

We require a two year commitment to this role

Qualifications

Bachelor's degree in clinical/medical laboratory science (CLS/MLS), medical technology (MT), chemistry, biological science from an accredited institution or bachelor’s degree from an accredited institution in addition to a certificate in MLS. Six years of relevant laboratory experience; or a Master's degree from an accredited institution in chemical, physical, biological, clinical laboratory science or medical technology and four years of relevant laboratory experience; or a Doctoral degree in chemistry or a biological science and two years of relevant laboratory experience. A HEW certificate may be substituted for the specified degree. Other clinical laboratory specialty certificates will be reviewed and approved on a case‑by‑case basis. Master's degree or Doctoral (PhD) degree from an accredited institution in chemical, physical, biological, clinical laboratory science or medical technology preferred. Test development/innovation leader for multiple complex cross-area projects.

Additional Qualifications

• Demonstrated ability to work independently with a high degree of initiative, organization, and efficiency while exercising sound judgment, decision‑making, and project management skills.
• Excellent written and verbal communication skills, with the ability to effectively collaborate across multidisciplinary teams.
• Proven ability to interpret and apply scientific literature, reference materials, and existing methodologies to develop and implement innovative laboratory methods, processes, or products.
• Adaptable and flexible in managing multiple projects involving diverse technologies, platforms, and scientific disciplines.
• Strong analytical, problem‑solving, and scientific expertise with comprehensive knowledge of laboratory procedures and best practices.
• Extensive experience with Next Generation Sequencing (NGS) technologies, including assay development, optimization, validation, and data interpretation.

License or Certification:

ASCP or other certification pertinent to the laboratory field may be required depending on the laboratory specialty and prevailing regulatory requirements. Employees obtaining CT certification(s) after January 1, 2004 will be required to demonstrate evidence of ongoing maintenance of certification. Employees obtaining SCT certification(s) after January 1, 2006 will be required to demonstrate evidence of ongoing maintenance of certification.

Exemption Status

Exempt

Compensation Detail

$85,467 - $128,252/ year

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

Schedule Details

Typically, Monday-Friday day shift with some flexibility for hours. Potential for some intermittent remote work as projects allow.

Weekend Schedule

No regularly scheduled weekends but could possibly be required based on specific project needs.

International Assignment

No

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'. Mayo Clinic participates inE-Verifyand may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.