Principal Data Scientist (R) – CDISC & Clinical Trials

ClinChoice; United States; Remote; USD 120,000 - 180,000; Full time

Job summary

ClinChoice is seeking a Principal Data Scientist Consultant with strong R skills and clinical programming expertise to join one of our clients. The role focuses on SDTM and ADaM datasets using CDISC standards, with SAS for legacy studies as needed.

You will develop reproducible R scripts, support TLF generation, QC checks, and collaborate with biostatistics and data management teams to ensure regulatory compliance for trials conducted in the United States.

Qualifications

• Bachelor’s or Master’s degree in Statistics, CS, Mathematics, Life Sciences, or related field.
• 4–6+ years of experience in clinical programming with a strong focus on R.
• Proven experience in creating SDTM and ADaM datasets using R.
• Working knowledge of SAS programming.
• Solid understanding of CDISC standards (SDTM, ADaM).
• Experience with clinical trial data, regulatory submissions, and QC processes.
• Strong analytical, problem-solving, and documentation skills.

Responsibilities

• Develop, validate, and maintain SDTM/ADaM datasets using R per CDISC standards.
• Support Tables, Listings, and Figures generation in R or SAS as needed.
• Write efficient, reproducible R scripts for clinical data analysis and reporting.
• Collaborate with statisticians, data managers, and clinical teams to define requirements.
• Perform QC checks, reconcile data issues, and ensure regulatory deliverables.
• Contribute to workflows, documentation, and version control best practices.
• Support automation initiatives and R-based pipeline development.
• Utilize SAS for legacy studies where required.

Skills

R scripting

SAS programming

CDISC standards

SDTM/ADaM datasets

Regulatory submissions

QC checks

Documentation

Team collaboration

Education

Bachelor's or Master’s in relevant field

Tools

Git

R Markdown

Shiny

CDISC tooling

Job description

ClinChoice is seeking a Principal Data Scientist Consultant with strong R skills and clinical programming expertise to join one of our clients. The role focuses on SDTM and ADaM datasets using CDISC standards, with SAS for legacy studies as needed.

You will develop reproducible R scripts, support TLF generation, QC checks, and collaborate with biostatistics and data management teams to ensure regulatory compliance for trials conducted in the United States.