Principal Data Engineer

Takeda Pharmaceuticals; Boston (MA); Remote; USD 139,000 - 237,000; Full time

Benefits offered by this job

Medical, dental, vision insurance

401(k) with match

Paid time off

Job summary

Takeda Development Center Americas, Inc. is seeking a Principal Data Engineer in Cambridge, MA with 100% remote work option across the U.S. You will lead cloud data pipelines, AI/ML initiatives, and real-time dashboards to support clinical and operational decision-making.

The role requires a Master’s degree in a related field and hands-on experience with Python, Spark, Airflow, and SQL. You will mentor engineers, drive automation, and collaborate with cross-functional teams to advance

Qualifications

• Master’s degree in Computer Science, Data Science, Engineering, or related field.
• Experience designing and deploying data engineering software.
• Strong knowledge of Python, Spark, and SQL required.
• Familiarity with AI/ML workflows and NLP is a plus.
• Experience in Agile/Scrum ceremonies and cross-functional collaboration.

Responsibilities

• Engineer cloud-based data pipelines using Python, Spark, and Airflow for ETL/ELT.
• Design and implement AI/ML and GenAI solutions to improve data quality.
• Develop robust data integration workflows and SQL-based validation.
• Create dashboards and real-time visuals for clinical and operational data.
• Develop automation tools using Python, R, and APIs to streamline data tasks.
• Partner with cross-functional teams, mentor junior engineers, advise leadership.
• Present technical innovations and guide enterprise adoption of scalable data solutions.

Education

Master’s degree in Computer Science, Data Science, Engineering, or related field

Tools

Python

Spark

Airflow

SQL

Selenium

Job description

Job Description

Pursuant to Section 20 C.F.R. 656.10, you are hereby notified that an application for Alien Employment Certification will be filed by Takeda Development Center Americas, Inc. for the following job opportunity:

JOB LOCATION

Cambridge, MA

POSITION

Principal Data Engineer

POSITION DESCRIPTION

Takeda Development Center Americas, Inc. is seeking a Principal Data Engineer with the following duties:

• engineer cloud-based data pipelines using Python, Spark, and Airflow to automate ETL/ELT processes, enabling efficient data ingestion, transformation, and storage across data lakes and warehouses
• design and implement AI/ML and GenAI-driven solutions using supervised/unsupervised learning, statistical modeling, and NLP to enhance data quality, automate workflows, detect similarities, and support evidence-based clinical decision-making
• develop robust data integration workflows for structured and unstructured data, ensuring adherence to Good Clinical Practices (GCP), FDA regulations, and SOPs through SQL-based data validation frameworks
• create interactive dashboards and real-time visualization platforms to deliver actionable insights from clinical and operational data, enabling stakeholders to monitor performance and drive data-informed strategies
• develop custom automation tools using Python, R, and APIs to streamline data entry, reduce manual processing, and enhance operational efficiency across clinical research systems
• drive strategic alignment by partnering with crossfunctional teams, mentoring junior engineers, and advising leadership on AI/ML adoption, automation strategies, and emerging data technologies
• influence industry practices by presenting technical innovations at leading conferences and guiding enterprise-wide adoption of scalable, AI-powered data engineering solutions

100% remote work allowed anywhere in the U.S.

Full time. $139,000 - $236,800 per year.

U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

REQUIREMENTS

• Master’s degree in Computer Science, Data Science, Engineering, or related field, plus 30 months of related experience.
• design, develop, test, and deploy software applications and features based on client and project requirements;
• implement automated testing and regression testing using Selenium and Python to improve test coverage, reduce manual effort, and ensure application stability;
• collaborate with cross-functional teams, including developers, business analysts, and QA leads, to identify test requirements and participate in Agile/Scrum ceremonies to plan, deliver, and communicate software progress iteratively;
• perform data wrangling, transformation, and management to create structured datasets stored in databases, supporting data analyses.

Additional Information

Locations: Boston, MA

Worker Type: Employee

Worker Sub-Type: Regular

Time Type: Full time