Principal Clinical Scientist

Alignerr Corp.; United States; Remote; AUD 138,000 - 248,000; Part time

Job summary

Alignerr Corp. is seeking a Principal Clinical Scientist (AI Training) to bring senior clinical and regulatory expertise to cutting-edge AI development.

You will help ensure AI models handling clinical data meet real-world regulatory standards, working remotely on a flexible hourly contract. You will design and review protocols, interpret trial results for regulatory relevance, and provide structured feedback to improve AI reasoning about clinical evidence, all while maintaining strict

Qualifications

• Senior-level experience designing and reviewing clinical trial protocols for regulatory submission.
• Deep expertise interpreting clinical data for regulatory agencies (FDA/EMA or equivalents).
• Strong background in clinical research methodology and biostatistics.
• Rigorous, detail-oriented with ability to critique scientific content.
• Ability to provide structured written feedback on AI-derived clinical analyses.

Responsibilities

• Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems.
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance.
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory alignment.
• Provide expert, structured feedback to help AI models reason accurately about trial data and evidence.
• Flag errors, inconsistencies, and methodological gaps in AI-generated clinical content.
• Work independently and asynchronously — fully on your own schedule.

Skills

Clinical trial design

Regulatory submissions

Regulatory science

Biostatistics

Critical thinking

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your hard-won expertise in clinical trial design and regulatory science could directly shape how AI reasons about medical evidence — influencing the next generation of biomedical AI systems used by researchers and clinicians worldwide?

We're looking for a Principal Clinical Scientist to bring senior-level clinical and regulatory knowledge into cutting-edge AI development. You'll work with Alignerr — a team that partners with the world's leading AI research labs — to ensure that AI models handling clinical data meet the rigorous standards of real-world regulatory science.

This is a fully remote, flexible contract role. No AI background needed — just deep clinical expertise and a sharp eye for scientific quality.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations from agencies such as the FDA, EMA, or equivalent
• Provide expert, structured feedback that helps AI models reason more accurately about clinical trial data, outcomes, and evidence
• Flag errors, inconsistencies, and methodological gaps in AI-generated clinical content
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing and reviewing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong background in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold clinical content to the highest standards
• Comfortable evaluating scientific reasoning and providing clear, structured written feedback
• No prior AI or tech experience required

Nice to Have

• Experience with data annotation, data quality review, or evaluation systems
• Background in pharmacology, medical affairs, or clinical operations
• Familiarity with AI tools or scientific content evaluation workflowsExperience spanning multiple therapeutic areas or regulatory jurisdictions

Why Join Us

• Work directly on frontier AI systems that are shaping the future of clinical and biomedical research
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, high-stakes expert work
• Collaborate with leading AI research teams on problems that matter
• Potential for ongoing work and contract extension as new projects launch