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McKesson Corporation is seeking a Principal AI Engineer to drive the multi-year strategy for our AI platform, spanning model strategy, RAG, tool ecosystems, and governance. You will lead architecture, risk assessment, and executive alignment across multiple teams in a regulated healthcare setting.
The role requires deep hands-on experience with production-scale LLMs, strong software fundamentals, and the ability to influence senior stakeholders without direct authority.
McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve - we care.
What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow's health today, we want to hear from you.
The Principal AI Engineer provides the highest level of individual-contributor technical leadership for the company's AI platform, operating one level above the Lead AI Engineer role. This person sets the multi-year architecture strategy for agentic and LLM-powered systems - spanning model strategy, retrieval-augmented generation (RAG), tool/connector ecosystems, and evaluation/governance tooling - across every team that builds on the AI platform, not just one. In a highly regulated healthcare environment, the Principal AI Engineer resolves the hardest, most ambiguous technical problems facing the platform, is a primary technical voice with executive leadership on AI strategy and risk, and shapes how the entire engineering organization adopts AI safely and effectively.
Success is measured by the durability and adoption of the technical strategy this role sets across multiple teams, this role's ability to unblock cross-organizational technical risk before it becomes a delivery or compliance problem, and its influence on AI investment decisions at the executive level.
Priority will be given to candidates who reside in the Columbus, OH metropolitan area.
We are unable to provide sponsorship for this role, presently or in the future.
We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, pleaseclick here.
Our Base Pay Range for this position
$195,000 - $325,000
McKesson is an Equal Opportunity Employer
McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson's full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.
McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.
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