Preclinical Mathematical Modeling Internship

AstraZeneca plc; Cambridge (MA); On-site; USD 42,000 - 60,000; Full time

Job summary

AstraZeneca plc is seeking a Preclinical Mathematical Modeling Summer Intern in Cambridge, MA, to support the Drug Metabolism and Pharmacokinetics within Oncology R&D. The role is a full-time dry-lab internship for rising sophomores/juniors, focusing on extending a modeling framework and exploring biological mechanisms using MATLAB.

The internship covers literature review, development of ODEs, and parameter sensitivity analysis, with onsite work in Kendall Square and a strict intern schedule

Qualifications

• Undergrad student pursuing a related engineering or science major.
• Rising sophomore (graduation 2029) or rising junior (graduation 2028).
• Applied or proficient skills in programming and data analysis.
• MATLAB coding proficiency preferred.

Responsibilities

• Review literature to inform the modeling framework.
• Develop ordinary differential equations to describe biological mechanisms.
• Perform parameter sensitivity analysis on model outputs.

Skills

Programming & data analysis

Teamwork

Verbal & written communication

Education

Undergraduate student in Biological Engineering, Biology, Mathematics, Physics, CS, Biochemistry or related field

Tools

MATLAB

Job description

AstraZeneca is seeking a Preclinical Mathematical Modeling Summer Intern to support the Drug Metabolism and Pharmacokinetics, Oncology team within Oncology Research & Development. Based in Kendall Square in Cambridge, Massachusetts, this full-time, dry-lab internship offers a rising sophomore or rising junior the opportunity to contribute to a specialized short-term project supporting capability development or key business initiatives. The intern will review scientific literature, extend an existing modeling framework, and use MATLAB to explore biological mechanisms through ordinary differential equations and parameter sensitivity analysis.

Key Responsibilities

• Review relevant scientific literature to inform additions to the current modeling framework.
• Develop ordinary differential equations to describe pertinent biological mechanisms.
• Perform parameter sensitivity analysis on resulting model outputs.

Required Qualifications

• Undergraduate student pursuing Biological Engineering, Biology, Mathematics, Physics, Computer Science, Biochemistry or related engineering majors.
• Rising sophomores, with anticipated graduation in 2029, or rising juniors, with anticipated graduation in 2028.
• Applied or proficient skills in programming and data analysis.
• MATLAB coding proficiency is preferred.
• Ability to work effectively both independently and as part of a team.
• US Work Authorization is required at time of application. Applicants must have work authorization that does not now or in the future require sponsorship of a visa.
• This role will not be providing CPT or OPT letters of support.
• Excellent verbal, written, and interpersonal communication skills are essential.
• Candidates must adhere to the intern program schedule June 7, 2027- August 13, 2027.
• Ability to report onsite to Cambridge, MA 3 days a week. This role will not provide relocation assistance.
• Hourly range: $37 per hour

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Date Posted

23-Oct-2026

Closing Date

12-Nov-2026

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