Postdoctoral Scientist – Mitochondrial Biology

Upenn; Philadelphia (Philadelphia County); On-site; USD 55,000 - 70,000; Full time

Job summary

The Bomba-Warczak Laboratory at the University of Pennsylvania is recruiting postdoctoral scientists to lead new research projects in mitochondrial biology. The role emphasizes independence, collaboration, and mentorship within a highly collaborative environment.

The lab at the Perelman School of Medicine’s Department of Physiology uses mouse models, quantitative biochemistry, and omics to uncover mitochondrial maintenance mechanisms, with access to proteomics, metabolomics, imaging, and mouse

Qualifications

• PhD in Biology, Biochemistry, Cell Biology, Physiology, Neuroscience, or related field.
• At least one first-author primary research publication in a peer-reviewed journal.
• Strong experimental and analytical skills in molecular or cellular biology.
• Ability to independently design and execute experiments.
• Experience with mitochondrial biology preferred.

Responsibilities

• Lead new research projects in mitochondrial biology.
• Collaborate within a highly collaborative team and mentor junior researchers.
• Contribute to experimental design, data analysis, and interpretation of results.

Skills

Mitochondrial biology experience

Molecular/cellular biology skills

Independent experiment design

Education

PhD in Biology/related field

Tools

Mass spectrometry / omics

Job description

Overview

The Bomba-Warczak Laboratory at the University of Pennsylvania is recruiting creative, collaborative, and highly independent Postdoctoral Scientists to lead new research projects in mitochondrial biology.

Our lab investigates how mitochondria are maintained and renewed in long-lived mammalian cells, with interest in sustaining organelle function over extended timescales in complex tissues. We integrate mouse models, quantitative biochemistry, stable-isotope tracing, and mass-spectrometry–based omics to understand the molecular mechanisms that govern mitochondrial maintenance, bioenergetics, and cellular resilience. Learn more about the lab at bombawarczaklab.com.

Projects will be tailored to the interests of the successful candidate within broadly defined research themes including:

• Mechanisms of mitochondrial maintenance and renewal in long-lived cells
• Molecular coordination of mitochondrial gene expression and protein homeostasis
• Systems-level analysis of mitochondrial metabolism and proteome dynamics
• Mitochondrial function in complex mammalian tissues, including the nervous system

The Bomba-Warczak Lab is based at the Perelman School of Medicine's Department of Physiology at the University of Pennsylvania, within a highly collaborative scientific environment that provides access to world-class facilities for proteomics, metabolomics, imaging, and mouse genetics. Our lab emphasizes rigorous science, intellectual independence, and strong mentorship supporting diverse career trajectories.

Qualifications

Required Qualifications

• PhD in Biology, Biochemistry, Cell Biology, Physiology, Neuroscience, or a related field
• Demonstrated research experience in mitochondrial biology
• At least one first-author primary research publication in a peer-reviewed journal
• Strong experimental and analytical skills in molecular or cellular biology
• Ability to independently design and execute experiments

Preferred Qualifications

• Experience working with mammalian systems and/or mouse models
• Exposure to mass spectrometry, proteomics, metabolomics or stable-isotope tracing or metabolic analysis
• Background in neuroscience or complex tissue physiology
• Computational/data analysis skills (R, Python, or similar)

EEO Statement

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.