Postdoctoral Scholar: Targeted Cancer Drug Discovery

UT Health Sciences; Memphis (TN); On-site; USD 65,000 - 90,000; Full time

Job summary

The Department of Pharmaceutical Sciences at the University of Tennessee Health Sciences is seeking a Postdoctoral Scholar to support NIH-funded research programs focused on developing selective, non-cytotoxic inhibitors of N-glycosylation for the treatment of metastatic breast cancer.

The candidate will participate in multidisciplinary efforts spanning medicinal chemistry, cancer biology, glycobiology, and pharmacology.

Qualifications

• Ph.D. in chemistry, biochemistry, or related field.
• Experience with multistep organic synthesis and structure elucidation.
• Strong record of analytical technique use (NMR, LC-MS, HRMS, HPLC).

Responsibilities

• Designs, synthesizes, and evaluates novel inhibitors from natural product scaffolds for metastatic cancers.
• Plans and executes multistep organic syntheses using modern methods.
• Purifies and characterizes compounds with NMR, LC-MS, HPLC, and related techniques.
• Collaborates with interdisciplinary team for structure-based drug design and optimization.
• Prepares progress reports for the PI and presents findings in group meetings.
• Evaluates literature and technologies for potential application to ongoing work.
• Analyzes data, interprets results, and proposes subsequent strategies.
• Engages in professional development to stay current in synthetic organic chemistry and cancer research.
• Performs other duties as assigned.

Skills

Data analysis

Scientific communication

Project management

Purification techniques

Education

PhD in chemistry/biochemistry or related field

Tools

NMR spectroscopy

LC-MS

HRMS

HPLC

Job description

The Department of Pharmaceutical Sciences at the University of Tennessee Health Sciences is seeking a Postdoctoral Scholar to support NIH-funded research programs focused on developing selective, non-cytotoxic inhibitors of N-glycosylation for the treatment of metastatic breast cancer.

The candidate will participate in multidisciplinary efforts spanning medicinal chemistry, cancer biology, glycobiology, and pharmacology.