Postdoctoral Scholar, Radu Laboratory, Nuclear Medicine and Theranostics

University of California, Los Angeles; Los Angeles (CA); Vor Ort; USD 55.000 - 70.000; Vollzeit

Zusammenfassung

The laboratory of Professor Caius Radu at UCLA is seeking a highly motivated Postdoctoral Scholar to contribute to the development of RNA-LNP cancer immunotherapy platforms. The role focuses on mechanistic discovery and translation toward potential clinical application in cancer immunotherapy.

We seek exceptional scientists with a passion for fundamental science and translational impact, working within a collaborative environment that spans departments, institutes, and industry partners.

Aufgaben

• Design and conduct mechanistic and translational studies of RNA-LNP-based cancer immunotherapies.
• Characterize innate and adaptive immune responses in human and murine systems.
• Evaluate therapeutic efficacy in preclinical tumor models.
• Analyze and interpret experimental data.
• Contribute to manuscript preparation and publication.

Jobbeschreibung

The laboratory of Professor Caius Radu in the Department of Nuclear Medicine and Theranostics and the Department of Molecular and Medical Pharmacology at UCLA is seeking a highly motivated Postdoctoral Scholar to contribute to the development of novel RNA-lipid nanoparticle (RNA-LNP) cancer immunotherapy platforms.

Our research investigates the mechanisms governing innate and adaptive antitumor immunity, with a particular emphasis on dendritic cell biology, antigen-specific CD8⁺ T-cell responses, and murine and human immunology. We integrate mechanistic studies in human and murine immune systems with preclinical cancer models to develop innovative RNA-based immunotherapies for future clinical translation.

The Radu laboratory is affiliated with the Parker Institute for Cancer Immunotherapy (PICI) and the UCLA Health Jonsson Comprehensive Cancer Center (JCCC). Professor Radu also directs JCCC's Cancer Molecular Imaging, Nanotechnology, and Theranostics (CMINT) Research Program. These affiliations provide opportunities for interdisciplinary collaborations spanning fundamental cancer biology, immunology, and translational therapeutics.

We seek exceptional scientists who are passionate about fundamental discovery and driven to translate scientific insights into transformative cancer treatments..

The successful candidate will:

• Design and conduct mechanistic and translational studies of RNA-LNP-based cancer immunotherapies.
• Characterize innate and adaptive immune responses in human and murine systems.
• Evaluate therapeutic efficacy in preclinical tumor models.
• Analyze and interpret experimental data.
• Contribute to manuscript preparation and publication.
• Participate in collaborative and multidisciplinary research projects.

Research Environment and Mentorship

Our laboratory emphasizes scientific creativity, intellectual rigor, and collaborative discovery. We operate through a “team of teams” model, bringing together complementary expertise from academic laboratories and industry to address important scientific problems. Postdoctoral Scholars have substantial freedom to develop innovative approaches within our shared research objectives. We encourage unconventional ideas supported by strong scholarship and rigorous experimentation. We place particular importance on recruiting scientists who contribute to the success of their colleagues. Trainees are expected to engage intellectually beyond their own projects and learn how to build productive scientific collaborations. Our mentorship strategy emphasizes the development of scientific independence and leadership. We seek individuals with the potential to become leaders in the field of cancer immunotherapy who can identify important scientific problems, make significant discoveries, and ultimately build and lead successful research teams.