Postdoctoral Scholar (Biochemistry and Molecular Biology)

The Pennsylvania State University; State College (Centre County); On-site; USD 55,000 - 75,000; Full time

Benefits offered by this job

Competitive benefits package

Job summary

A leading research university is seeking a Postdoctoral Scholar to explore chromatin complexes using cryoelectron microscopy. Candidates should possess a Ph.D. and have experience in relevant fields such as cryoelectron microscopy and biochemistry. The role offers a chance to work in a collaborative, interdisciplinary environment with access to advanced microscopy tools.

Qualifications

• A Ph.D. is required by the appointment date.
• Prior experience with cryoelectron microscopy, macromolecular crystallography, chromatin biology or biochemistry is preferred.
• Preference will be given to applicants who have received their Ph.D. degree within the last three years.

Responsibilities

• Determine the structures of chromatin complexes using cryoelectron microscopy.
• Co-express complexes in vivo.
• Reconstitute chromatin complexes in vitro.

Skills

cryoelectron microscopy

macromolecular crystallography

chromatin biology

biochemistry

Education

Ph.D.

Tools

Cryo-EM facilities

Job description

APPLICATION INSTRUCTIONS

• CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, apply internally through Workday.
• CURRENT PENN STATE STUDENT (not employed previously at the university) and seeking employment with Penn State, please login to Workday to complete the student application process. Please do not apply here, apply internally through Workday.
• If you are NOT a current employee or student, please click "Apply" and complete the application process for external applicants.

Approval of remote and hybrid work is not guaranteed regardless of work location. For additional information on remote work at Penn State, see Notice to Out of State Applicants.

This is a term position; length of the term will be discussed during the interview process. Continuation past the term length discussed will be based on university need, performance, and/or availability of funding.

POSITION SPECIFICS

The Laboratory of Song Tan in the Department of Biochemistry & Molecular Biology and the Center for Eukaryotic Gene Regulation at Penn State seeks a Postdoctoral Scholar to determine the structures of chromatin complexes using cryoelectron microscopy. We are interested in epigenetic chromatin enzymes or transcription factors in complex with their nucleosome targets.

Our research efforts are enhanced by:

1. Techniques we have developed to co-express complexes in vivo
2. Techniques to reconstitute chromatin complexes in vitro
3. Excellent access to Penn State's Titan Krios and Arctica electron microscopes both equipped with Falcon 4 detectors.

The Center for Eukaryotic Gene Regulation is a highly collaborative and interdisciplinary environment which includes the groups of Drs. Jean-Paul Armache, Lu Bai, Manyu Du, Marina Feric, Scott Lindner, Manuel Llinas, Shaun Mahony, Joe Reese, Scott Showalter and Song Tan, each with research programs targeted at understanding the molecular basis for gene regulation on chromatin templates.

Education and Experience

A Ph.D. is required by the appointment date.

Electron Microscopes, Crystallographers, Molecular Biologists and Biochemists with a Ph.D. are encouraged to apply. Prior experience with cryoelectron microscopy, macromolecular crystallography, chromatin biology or biochemistry is preferred. Preference will be given to applicants who have received their Ph.D. degree within the last three years.

Applications should be submitted electronically and should include a cover letter describing research experience and interests, curriculum vitae and contact information for three references. Review of applications will begin immediately and continue until positions are filled.

BACKGROUND CHECKS/CLEARANCES

Employment with the University will require successful completion of background check(s) in accordance with University policies.

BENEFITS

Penn State provides a competitive benefits package for full-time employees designed to support both personal and professional well-being.

For more detailed information, please visit our Benefits Page.

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EEO IS THE LAW

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