POSTDOCTORAL RESEARCHER - Program in Memory Longevity - Losonczy Lab

The University of Texas Southwestern Medical Center; Dallas (TX); On-site; USD 52,000 - 70,000; Full time

Benefits offered by this job

PPO medical plan

Paid Time Off

Retirement Programs

Paid Parental Leave

Job summary

UT Southwestern Medical Center in Dallas seeks applications for multiple postdoctoral fellow positions to investigate memory mechanisms in the mammalian brain using molecular, cellular, or imaging approaches in animal models and human tissue. The successful applicant will be embedded in the Neuroscience community at UT Southwestern and OBI, with collaborations across the US and Europe.

This is a full-time postdoctoral fellow position in a neurobiology laboratory focusing on learning and memory

Qualifications

• Ph.D. in Neuroscience, Cell Biology, Biochemistry, Physics, Electrical Engineering, Statistics, Computer Science or a related field.

Responsibilities

• Characterize synaptic and dendritic integration and plasticity in mouse and human hippocampal neurons using patch-clamp and imaging.
• Explore learning-related plasticity in vivo and in vitro through multi-omics approaches.
• Investigate memory mechanisms in mammalian brain with molecular, cellular, or imaging methods.

Skills

Patch-clamp recording

Slice electrophysiology

Cell culture electrophysiology

In vivo two-photon imaging

In vivo calcium imaging

Molecular neurobiology techniques

Education

Ph.D. in Neuroscience or related field

Tools

MATLAB

Python

Proteomics

Transcriptomics

Genomics

Bioinformatics

Job description

Program for Memory Longevity (PML), led by Attila Losonczy, MD, PhD, in the O’Donnell Brain Institute (OBI) and the Department of Neuroscience at the University of Texas Southwestern (UTSW) Medical Center in Dallas, seeks applications for multiple postdoctoral fellow positions to investigate memory mechanisms in the mammalian brain using innovative molecular, cellular, or imaging approaches in animal models and human tissue. The successful applicant will be embedded in the larger Neuroscience community at UTSW and OBI, and will benefit from a network of collaborations with research groups in the US and Europe.

This is a full-time postdoctoral fellow position in a neurobiology laboratory focusing on the synaptic and cellular/molecular mechanisms of learning and memory.

Potential projects include:

• In vitro electrophysiology and imaging: Characterizing synaptic and dendritic integration and plasticity of mouse and human hippocampal neurons using patch-clamp recording, single-cell electroporation, Patch-seq, and advanced imaging approaches.
• In vivo imaging: Characterizing synaptic plasticity during navigation and learning using two-photon calcium, voltage, and neurotransmitter imaging.
• Molecular neurobiology: Characterizing learning related plasticity in vivo and in vitro through multi-omics approaches (e.g., transcriptomics, proteomics).

Required qualifications:

• In vitro electrophysiology: Proficiency in whole-cell patch clamp recording, acute slice preparation, and/or cell culture electrophysiology, along with related data analysis methods using tools such as MATLAB or Python.
• In vivo imaging: Proficiency with in vivo two-photon calcium and/or voltage imaging techniques, including experimental execution and data analysis.
• Molecular neurobiology: Proficiency with techniques such as proteomics, transcriptomics and genomics, and related bioinformatics and statistical analysis techniques.

Candidates must hold a Ph.D. in Neuroscience, Cell Biology, Biochemistry Physics, (Electrical) Engineering, Statistics, Computer Science or a related field.

UTSouthwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis ofrace, color, religion, national origin, sex,sexual orientation, gender identity, gender expression,age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/

Benefits

UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

• PPO medical plan, available day one at no cost for full-time employee-only coverage
• 100% coverage for preventive healthcare – no copay
• Paid Time Off, available day one
• Retirement Programs through the Teacher Retirement System of Texas (TRS)
• Paid Parental Leave Benefit
• Wellness programs
• Tuition Reimbursement
• Public Service Loan Forgiveness (PSLF) Qualified Employer
• Learn more about these and other UTSW employee benefits!