Postdoctoral Research Fellow (Danzer) Tuberous Sclerosis

CO00 Children's Hospital Medical Center; United States; On-site; USD 55,000 - 70,000; Full time

Job summary

CO00 Children's Hospital Medical Center is seeking a Postdoctoral Fellow in Cincinnati to conduct phenotype-genotype studies using human iPSCs. This role focuses on understanding epileptogenesis mechanisms in tuberous sclerosis complex and enhancing patient care.

The ideal candidate should hold a PhD/MD in Neuroscience, possess skills in experimental design and data analysis, and have at least two years of relevant experience. The position requires full-time commitment with a day shift schedule.

Qualifications

• At least two years of experience conducting human iPSC work.
• Strong experimental design, data analysis, and scientific writing skills.
• Experience with advanced experimental techniques is preferred.

Responsibilities

• Develop critical thinking and analytical skills to become an independent scientist.
• Design, execute, record laboratory experiments, and analyze data.
• Mentor research staff and manage fiscal responsibilities.
• Present research at meetings and prepare scientific reports.

Skills

Experimental design

Data analysis

Scientific writing

Communication skills

Teamwork skills

Education

Doctoral degree (PhD/MD) in Neuroscience or related field

Tools

EEG

Optogenetics

Chemogenetics

AAV

Transgenic approaches

Calcium imaging

Job description

Postdoctoral Fellow – Danzer Laboratory

The Danzer laboratory at Cincinnati Children’s and the University of Cincinnati Medical Center is seeking a postdoctoral fellow to conduct phenotype‑genotype studies using human iPSCs to characterize patient mutations for children with tuberous sclerosis complex (TSC). The focus is on elucidating basic mechanisms of epileptogenesis in mTORopathies and improving patient care. The lab uses a wide variety of model systems and experimental approaches, including EEG, multi‑unit recording, optogenetics, chemogenetics, AAV, transgenic approaches, calcium imaging, confocal and light sheet microscopy, and electrophysiology.

Responsibilities

• Develop critical thinking and analytical skills to become an independent scientist.
• Design, execute, record laboratory experiments, and analyze data.
• Research and improve current methods, evaluate innovative techniques, and maintain protocol and assay accuracy.
• Implement knowledge in the Division/Department, troubleshoot equipment, and correct erroneous results.
• Present research at meetings, journal clubs, seminars; prepare scientific reports, papers, abstracts, and grant proposals.
• Mentor research staff and manage fiscal responsibilities.
• Maintain currency in the field through continuing education, literature review, and seminars.
• Attend required Cincinnati Children’s training sessions and ensure regulatory compliance with institutional policies.
• Perform other duties as assigned.

Qualifications

• Doctoral degree (PhD/MD) in Neuroscience or a closely related field.
• At least two years of experience conducting human iPSC work.
• Strong experimental design, data analysis, and scientific writing skills.
• Experience with EEG, optogenetics, chemogenetics, AAV, transgenic approaches, calcium imaging, etc. is preferred.
• Excellent communication and teamwork skills.

Location

Primary Location: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH – full‑time, day shift (40 hours per week).

Equal Opportunity Statement

Cincinnati Children’s is a proud Equal Opportunity Employer committed to creating an environment of dignity and respect for all employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability, or protected veteran status.